Results 101 to 110 of about 16,537,979 (373)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Tuberculin Skin Testing in Children

open access: yesEmerging Infectious Diseases, 2006
In 1996, the American Academy of Pediatrics (AAP) recommended targeted tuberculin skin testing (TST) of children while discouraging routine TST of children without risk factors for tuberculosis (TB). Recent studies have provided evidence in support of the targeted TST and recommendations that favor risk assessment over universal screening with TST ...
Marina Reznik, Philip O. Ozuah
openaire   +4 more sources

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

Titanium honeycomb acoustic lining structural and thermal test report [PDF]

open access: yes
The results are presented of static, fatigue and thermal testing of titanium honeycomb acoustic panels representing the acoustic tailpipe for the Pratt and Whitney Aircraft JT8D Refan engine which is being studied for use on the Boeing 727-200 airplane ...
Balut, J. P., Joynes, D.
core   +1 more source

Health Education Improve Behavior and Self-efficacy on Personal Hygiene Among Children with Intellectual Disability [PDF]

open access: yes, 2019
Personal hygiene is one of the basic human needs and must be kept clean, including scalp and hair, eyes, nose, ears, nails of hands and feet, skin and overall body care.
Akrom, A. (Akrom)   +3 more
core   +2 more sources

Comparing chest Radiograph and Tuberculin Skin Tests in Children [PDF]

open access: yesActa Medica Iranica, 2009
World Health organization (WHO) has reported that out of more than 10,000 of 250,000 tuberculosis afflicted children die annually. Pulmonary tuberculosis is a research priority in our country, and diagnos-ing this disease especially in children who are ...
Marzieh Pazoki   +5 more
doaj   +1 more source

Comparison of cell-mediated immunity due to Leishmania infantum promastigotes and axenic amastigotes

open access: yesVaccine Research, 2018
Introduction: Leishmania infantum is the causative agent of visceral leishmaniasis (VL). Cell-mediated immunity (CMI) is required to control leishmaniases. Therefore, simple tests that can evaluate the cellular immunity of the target populations can help
A Najafi-Dastanaei   +4 more
doaj  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Difference in proton radii of mirror nuclei as a possible surrogate for the neutron skin

open access: yes, 2017
It has been recently suggested that differences in the charge radii of mirror nuclei are proportional to the neutron-skin thickness of neutron-rich nuclei and to the slope of the symmetry energy $L$ [B.A. Brown Phys. Rev. Lett. 119, 122502 (2017)].
Piekarewicz, J., Yang, Junjie
core   +1 more source

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