Pilot study on the use of basophil activation tests and skin tests for the prevention of allergic transfusion reactions [PDF]
Background and objectivesManagement of severe allergic transfusion reactions (ATR) is challenging. In this study, we investigate the usefulness of skin tests and basophil activation tests (BAT) in chronically transfused patients for the prevention of ...
Philippe Akiki+12 more
doaj +2 more sources
Polyethylene Glycol and Polysorbate 80 Skin Tests in the Context of an Allergic Risk Assessment for Hypersensitivity Reactions to Anti-SARS-CoV-2 mRNA Vaccines [PDF]
Concern has arisen about hypersensitivity reactions in patients with allergic reactions to drugs containing polyethylene glycol (PEG) or polysorbate 80 (PS80), excipients of currently available anti-SARS-CoV-2 mRNA vaccines.
Emanuele Nappi+12 more
doaj +2 more sources
Renin-angiotensin系は腎性高1血圧の昇圧機構を説明しようとする一つの興味ある所見である.本態性および腎性高血圧者,特にその急性期では,血中のangiotensin量が増加し,末梢血管のangiotensinに対する反応性が増強しているといわれている.著者らは高血圧の成因が異なるに従い,生体のangiotensinに対する反応が異なるのではないかとの想定の下に,α-1 asp-5 val-angiotensin IIおよびβ-1 asp-5val-angiotensin IIを用い,正常者並びに高血圧者に皮内反応を行なつた.本態性および腎性高血圧患者では,正常血圧者に比し本反応の持続時間の延長を認め,それに反し大動脈硬化に由来すると思われる心・血管性高血圧では延長しないことを認めた ...
Tatsuo Kokubu+2 more
openalex +5 more sources
Development of Biofidelic Skin Simulants Based on Fresh Cadaveric Skin Tests [PDF]
The development of artificial skin that accurately mimics the mechanical properties of human skin is crucial for a wide range of applications, including surgical training for burn injuries, biomechanical testing, and research in sports injuries and ...
Gurpreet Singh+2 more
doaj +2 more sources
Anaphylaxis due to midazolam administered before induction of general anesthesia: a case report [PDF]
Background Anaphylaxis is an immediate allergic reaction. However, in some cases, there is a delay between the administration of the causative agent and the onset of anaphylaxis.
Ryosuke Funabiki+5 more
doaj +2 more sources
Prick, patch or blood test? A simple guide to allergy testing [PDF]
This article provides information on allergy testing and serves as a simple guide for physicians who are considering using allergy testing as a step in patient management.
Leelavathi Muthupalaniappen+1 more
doaj +1 more source
Beta-lactam (BL) drugs are the antibiotics most prescribed worldwide due to their broad spectrum of action. They are also the most frequently implied in hypersensitivity reactions with a known specific immunological mechanism. Since the commercialization
María del Valle Campanón Toro+11 more
doaj +1 more source
Drug allergy evaluation in children with suspected mild antibiotic allergy
BackgroundAdverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit ...
Nikolaos Kitsos+7 more
doaj +1 more source
Histoplasmosis: To Skin Test or Not to Skin Test?
SummaryA single skin test with commercially-available histoplasmin did not stimulate significant antibody response in the sera of 187 persons when measured by the yeast phase complement-fixation, collodion agglutination or histoplasmin latex agglutination tests.
Robert L. Perkins+3 more
openaire +3 more sources
Testes cutâneos de hipersensibilidade imediata com o evoluir da idade Positive skin test and age
OBJETIVO: avaliação da positividade aos testes cutâneos de hipersensibilidade imediata em crianças com asma brônquica e/ou rinite alérgica em diferentes faixas etárias.
Wilma Carvalho Neves Forte+6 more
doaj +1 more source