Results 21 to 30 of about 17,654,957 (400)
Skin tests in the diagnosis of drug hypersensitivity reactions.
Adverse drug reactions (ADRs) are an area of concern for pharmaceutical drug development. Among these, drug hypersensitivity reactions are neither dose-dependent nor predictable, and affect only predisposed individuals. Clinical and immunological studies
Brockow, K;Romano, A
core +2 more sources
Drug allergy evaluation in children with suspected mild antibiotic allergy
BackgroundAdverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit ...
Nikolaos Kitsos +7 more
doaj +1 more source
Among 74 patients with an immediate hypersensitivity reaction (IHR) to iodinated contrast media (ICM), the rate of allergic patients confirmed by positive prick test or diluted intradermal test (IDT) was 8.1%. 12.5% of re‐exposed patients had a recurrent
Juliette Caron +2 more
doaj +1 more source
Factors affecting microneedle insertion into skin are reviewed. The use of artificial and computational skin models for the simulation of needle insertion is summarized.
Pooyan Makvandi +10 more
semanticscholar +1 more source
Histoplasmosis: To Skin Test or Not to Skin Test?
SummaryA single skin test with commercially-available histoplasmin did not stimulate significant antibody response in the sera of 187 persons when measured by the yeast phase complement-fixation, collodion agglutination or histoplasmin latex agglutination tests.
S, Saslaw +3 more
openaire +2 more sources
Assessment of drug hypersensitivity with non-irritating concentrations of antibacterial agents for allergic skin tests: a review [PDF]
Hypersensitivity reactions to antibiotics are common with a prevalence of 6-10% of all adverse reactions. There is a lack of guidelines and standardization of skin tests for the screening of hypersensitivity to all antibiotics, in terms of the ...
M. C., Shivamurthy +2 more
core +1 more source
Goal of the study: to define efficiency of tuberculous infection detection in children from 8 to 17 years old basing on the results of screening with recombinant tuberculous allergen skin test (RTA).Materials and methods.
S. V. Zubareva, E. N. Turkin
doaj +1 more source
The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian +4 more
core +1 more source
Testes cutâneos de hipersensibilidade imediata com o evoluir da idade Positive skin test and age
OBJETIVO: avaliação da positividade aos testes cutâneos de hipersensibilidade imediata em crianças com asma brônquica e/ou rinite alérgica em diferentes faixas etárias.
Wilma Carvalho Neves Forte +6 more
doaj +1 more source
Assessment of the potential skin irritation of lysine-derivative anionic surfactants using mouse fibroblast and human keratinocytes as an alternative to animal testing [PDF]
Purpose. The aim of this study was to identify new surfactants with low skin irritant properties for use in pharmaceutical and cosmetic formulations, employing cell culture as an alternative method to in vivo testing.
Vinardell, M. Pilar +7 more
core +1 more source

