Results 21 to 30 of about 17,654,957 (400)

Skin tests in the diagnosis of drug hypersensitivity reactions.

open access: yesCurrent pharmaceutical design, 2008
Adverse drug reactions (ADRs) are an area of concern for pharmaceutical drug development. Among these, drug hypersensitivity reactions are neither dose-dependent nor predictable, and affect only predisposed individuals. Clinical and immunological studies
Brockow, K;Romano, A
core   +2 more sources

Drug allergy evaluation in children with suspected mild antibiotic allergy

open access: yesFrontiers in Allergy, 2022
BackgroundAdverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit ...
Nikolaos Kitsos   +7 more
doaj   +1 more source

Immediate hypersensitivity reactions to iodinated contrast media: The diagnosis of allergy by skin testing

open access: yesClinical and Translational Allergy, 2022
Among 74 patients with an immediate hypersensitivity reaction (IHR) to iodinated contrast media (ICM), the rate of allergic patients confirmed by positive prick test or diluted intradermal test (IDT) was 8.1%. 12.5% of re‐exposed patients had a recurrent
Juliette Caron   +2 more
doaj   +1 more source

Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion

open access: yesNano-Micro Letters, 2021
Factors affecting microneedle insertion into skin are reviewed. The use of artificial and computational skin models for the simulation of needle insertion is summarized.
Pooyan Makvandi   +10 more
semanticscholar   +1 more source

Histoplasmosis: To Skin Test or Not to Skin Test?

open access: yesExperimental Biology and Medicine, 1967
SummaryA single skin test with commercially-available histoplasmin did not stimulate significant antibody response in the sera of 187 persons when measured by the yeast phase complement-fixation, collodion agglutination or histoplasmin latex agglutination tests.
S, Saslaw   +3 more
openaire   +2 more sources

Assessment of drug hypersensitivity with non-irritating concentrations of antibacterial agents for allergic skin tests: a review [PDF]

open access: yes, 2014
Hypersensitivity reactions to antibiotics are common with a prevalence of 6-10% of all adverse reactions. There is a lack of guidelines and standardization of skin tests for the screening of hypersensitivity to all antibiotics, in terms of the ...
M. C., Shivamurthy   +2 more
core   +1 more source

USE OF RECOMBINANT TUBERCULOUS ALLERGEN IN SCREENING FOR TUBERCULOUS INFECTION IN CHILDREN AND ADOLESCENTS

open access: yesТуберкулез и болезни лёгких, 2017
Goal of the study: to define efficiency of tuberculous infection detection in children from 8 to 17 years old basing on the results of screening with recombinant tuberculous allergen skin test (RTA).Materials and methods.
S. V. Zubareva, E. N. Turkin
doaj   +1 more source

The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]

open access: yes, 2010
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian   +4 more
core   +1 more source

Testes cutâneos de hipersensibilidade imediata com o evoluir da idade Positive skin test and age

open access: yesJornal de Pediatria, 2001
OBJETIVO: avaliação da positividade aos testes cutâneos de hipersensibilidade imediata em crianças com asma brônquica e/ou rinite alérgica em diferentes faixas etárias.
Wilma Carvalho Neves Forte   +6 more
doaj   +1 more source

Assessment of the potential skin irritation of lysine-derivative anionic surfactants using mouse fibroblast and human keratinocytes as an alternative to animal testing [PDF]

open access: yes, 2004
Purpose. The aim of this study was to identify new surfactants with low skin irritant properties for use in pharmaceutical and cosmetic formulations, employing cell culture as an alternative method to in vivo testing.
Vinardell, M. Pilar   +7 more
core   +1 more source

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