Pilot study on the use of basophil activation tests and skin tests for the prevention of allergic transfusion reactions [PDF]
Background and objectivesManagement of severe allergic transfusion reactions (ATR) is challenging. In this study, we investigate the usefulness of skin tests and basophil activation tests (BAT) in chronically transfused patients for the prevention of ...
Philippe Akiki+12 more
doaj +2 more sources
Polyethylene Glycol and Polysorbate 80 Skin Tests in the Context of an Allergic Risk Assessment for Hypersensitivity Reactions to Anti-SARS-CoV-2 mRNA Vaccines [PDF]
Concern has arisen about hypersensitivity reactions in patients with allergic reactions to drugs containing polyethylene glycol (PEG) or polysorbate 80 (PS80), excipients of currently available anti-SARS-CoV-2 mRNA vaccines.
Emanuele Nappi+12 more
doaj +2 more sources
Development of Biofidelic Skin Simulants Based on Fresh Cadaveric Skin Tests [PDF]
The development of artificial skin that accurately mimics the mechanical properties of human skin is crucial for a wide range of applications, including surgical training for burn injuries, biomechanical testing, and research in sports injuries and ...
Gurpreet Singh+2 more
doaj +2 more sources
Guidelines for performing skin tests with drugs in the investigation of cutaneous adverse drug reactions [PDF]
Skin testing with a suspected drug has been reported to be helpful in determining the cause of cutaneous adverse drug reactions (CADR). Many isolated reports of positive drug skin tests are published, but without detailed information concerning the ...
Barbaud, A+4 more
core +2 more sources
Prick, patch or blood test? A simple guide to allergy testing [PDF]
This article provides information on allergy testing and serves as a simple guide for physicians who are considering using allergy testing as a step in patient management.
Leelavathi Muthupalaniappen+1 more
doaj +1 more source
Renin-angiotensin系は腎性高1血圧の昇圧機構を説明しようとする一つの興味ある所見である.本態性および腎性高血圧者,特にその急性期では,血中のangiotensin量が増加し,末梢血管のangiotensinに対する反応性が増強しているといわれている.著者らは高血圧の成因が異なるに従い,生体のangiotensinに対する反応が異なるのではないかとの想定の下に,α-1 asp-5 val-angiotensin IIおよびβ-1 asp-5val-angiotensin IIを用い,正常者並びに高血圧者に皮内反応を行なつた.本態性および腎性高血圧患者では,正常血圧者に比し本反応の持続時間の延長を認め,それに反し大動脈硬化に由来すると思われる心・血管性高血圧では延長しないことを認めた ...
Tatsuo Kokubu+2 more
openalex +5 more sources
Skin tests in the work‐up of cutaneous adverse drug reactions: A review and update
Skin tests, including patch tests (PTs), prick tests, and intradermal tests (IDTs), are useful in identifying the culprits of cutaneous adverse drug reactions (CADRs), and determining safer, alternative drugs.
A. Barbaud, J. Castagna, A. Soria
semanticscholar +1 more source
Beta-lactam (BL) drugs are the antibiotics most prescribed worldwide due to their broad spectrum of action. They are also the most frequently implied in hypersensitivity reactions with a known specific immunological mechanism. Since the commercialization
María del Valle Campanón Toro+11 more
doaj +1 more source
Skin tests may induce DRESS relapse [PDF]
Said B+5 more
europepmc +3 more sources
Skin tests in the diagnosis of adverse drug reactions: a systematic review.
Adverse Drug Reactions (ADRs) are common and influence negatively the patient's therapeutic options. They recognize multiple pathogenic mechanisms, some of immunological origin, and the clinical manifestations involve several organs and systems ...
L. Stingeni+11 more
semanticscholar +1 more source