Cell-Type-Specific Differentiation and Molecular Profiles in Skin Transplantation: Implication of Medical Approach for Genetic Skin Diseases [PDF]
Skin is highly accessible and valuable organ, which holds promise to accelerate the understanding of future medical innovation in association with skin transplantation, engineering, and wound healing.
Noritaka Oyama, Fumio Kaneko
doaj +6 more sources
Murine Full-thickness Skin Transplantation. [PDF]
Murine full-thickness skin transplantation is a well-established in vivo model to study alloimmune response and graft rejection. Despite its limited application to humans, skin transplantation in mice has been widely employed for transplantation research.
Cheng CH+6 more
europepmc +6 more sources
Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. [PDF]
Among the mechanisms of suppression that T regulatory (Treg) cells exert to control the immune responses, the secretion of small extracellular vesicles (sEV) has been recently proposed as a novel contact‐independent immunomodulatory mechanism.
Campos-Mora M+8 more
europepmc +2 more sources
Murine skin transplantation. [PDF]
As one of the most stringent and least technically challenging models, skin transplantation is a standard method to assay host T cell responses to MHC-disparate donor antigens.
Kym R. Garrod, M. Cahalan
semanticscholar +4 more sources
Long-term Maintenance of Sterility Following Skin Transplantation in Germ-free Mice. [PDF]
Background There is considerable interest in investigating the role of the microbiota in various diseases, including transplant rejection. Germ-free (GF) and gnotobiotic mice are powerful models for this line of investigation, but performing surgery ...
Theriault B+5 more
europepmc +2 more sources
Transplantation of Actinically Damaged Skin
The aging skin has been under intense scrutiny in recent years. A variety of changes have been described clinically and histologically. The dry, leathery, wrinkled, weather-beaten skin of the farmer and sailor is familiar to all. This is associated with basophilic degeneration in the upper dermis and the appearance of fibers having the staining and ...
William Gerstein, Robert G. Freeman
openalex +4 more sources
TRANSPLANTATION OF SKIN IN PLASTIC OPERATIONS ON THE EYELID. [PDF]
The transplantation of skin flaps in plastic operations upon the eyelid, by the method in vogue at present, is the result of a gradual development in the size of the portions of new tissue to be transplanted. The method of supplying new dermal tissues where loss of skin had resulted from accidents, burns or other causes, was originally introduced by ...
Walter B. Johnson
openalex +5 more sources
Myeloablative autologous stem-cell transplantation for severe scleroderma [PDF]
BACKGROUND Despite current therapies, diffuse cutaneous systemic sclerosis (scleroderma) often has a devastating outcome. We compared myeloablative CD34+ selected autologous hematopoietic stem‐cell transplantation with immunosuppression by means of 12 ...
Brasington, R., et al,
core +3 more sources
Immunosuppression and Temporary Skin Transplantation in the Treatment of Massive Third Degree Burns
A method of burn treatment (immunosuppression and temporary skin transplantation) for patients suffering from massive third degree burns is evaluated. The method is based on the prompt excision of all dead tissue (burn eschar) and immediate closure of ...
John F. Burke+5 more
openalex +3 more sources
Skin transplantation in the foetal lamb. [PDF]
Skin autografts and homo grafts have been performed in foetal lambs between the ages of 80 and 117 days. By means of histological examination following grafting, visual and histological examinations after birth, and by the use of second-set homo grafts ...
P. Schinckel, K. Ferguson
semanticscholar +4 more sources