Results 41 to 50 of about 1,396,672 (205)

Eicosanoids in Skin Wound Healing

International Journal of Molecular Sciences, 2020
Wound healing is an important process in the human body to protect against external threats. A dysregulation at any stage of the wound healing process may result in the development of various intractable ulcers or excessive scar formation. Numerous factors such as growth factors, cytokines, and chemokines are involved in this process and play vital ...
Ken Yasukawa, Toshiaki Okuno, Takehiko Yokomizo   +2 more
openaire   +2 more sources

Low-detergent sonication decellularization preserves extracellular matrix architecture and enhances cell infiltration in human acellular dermal matrix

Frontiers in Bioengineering and Biotechnology
IntroductionAcellular dermal matrix (ADM) scaffolds support tissue regeneration by providing structural integrity, biological cues, and a permissive microenvironment; optimal ADMs integrate with native tissue while preserving extracellular matrix (ECM ...
Mzwandile Mbele, Tonétha Jay, Nonhlanhla P. Khumalo, Ardeshir Bayat   +3 more
doaj   +1 more source

YAP promotes the healing of ischemic wounds by reducing ferroptosis in skin fibroblasts through inhibition of ferritinophagy

Heliyon
The impaired healing of chronic wounds is often attributed to the ischemic and hypoxic microenvironment, leading to increased cell death. Ferroptosis, a novel form of cell death unveiled in recent years, could potentially be linked with the process of ...
Guoqi Cao, Siyuan Yin, Jiaxu Ma, Yongpan Lu, Ru Song, Zhenjie Wu, Chunyan Liu, Jian Liu, Peng Wu, Rui Sun, Aoyu Chen, Yibing Wang   +11 more
doaj   +1 more source

Skin wound healing as a mirror to cardiac wound healing

Experimental Physiology, 2023
Abstract Wound healing is a general response of the body to injury. All organs share in common three response elements to wound healing: inflammation to prevent infection and stimulate the removal of dead cells, active anti‐inflammatory signalling to turn off the inflammatory response, and a repair phase characterized by extracellular
Merry L. Lindsey, Mediha Becirovic‐Agic   +1 more
openaire   +4 more sources

Functional characterization of cultured keratinocytes after acute cutaneous burn injury. [PDF]

, 2012
In addition to forming the epithelial barrier against the outside environment keratinocytes are immunologically active cells. In the treatment of severely burned skin, cryoconserved keratinocyte allografts gain in importance.
Gerd G Gauglitz, Faist Eugen, Guido Henkel von Donnersmarck, Eugen Faist, v. Spiegel Felix, Spiegel, Felix von, Faist, Eugen, Zedler Siegfried, Siegfried Zedler, Felix von Spiegel, v. Donnersmarck Guido Henkel, Fuhr, Jasmin, Jasmin Fuhr, Gauglitz, Gerd, Henkel von Donnersmarck, Guido, Fuhr Jasmin, Zedler, Siegfried, Gauglitz Gerd G.   +17 more
core   +2 more sources

Metal gel particles loaded with epidermal cell growth factor promote skin wound repair mechanism by regulating miRNA

Open Chemistry, 2023
Skin wounds are prone to fungal infections and may threaten patients’ lives in severe cases. However, conventional treatment protocols rarely promote skin wound repair by modulating microRNA (miRNA). A novel binuclear cobalt(ii) complex with the chemical
Bian Yanfeng, Liu Shizhou, Huang Jing, Ma Tianlong   +3 more
doaj   +1 more source

Local and Remote Effects of Mesenchymal Stem Cell Administration on Skin Wound Regeneration

Pathophysiology, 2021
Wound healing is an important medical problem. We evaluated the efficacy of locally administered mesenchymal stem cells (MSCs) isolated from human umbilical cords on the dynamics of skin wound healing. The study was conducted on the backs of Wistar rats,
Ekaterina Silina, Victor Stupin, Konstantin Koreyba, Sergey Bolevich, Yulia Suzdaltseva, Natalia Manturova   +5 more
doaj   +1 more source

Biomimetic optimization of silicone breast implant integration: insights into wound healing and the foreign body response

Frontiers in Bioengineering and Biotechnology
Breast augmentation is the most prevalent aesthetic surgical procedure worldwide. While silicone breast implants have evolved in terms of safety and biocompatibility, they inevitably trigger a foreign body response (FBR). This complex process can lead to
Kevin Dzobo, Traci A. Wilgus, Vanessa Zamora Mora, Audry Zoncsich, Roberto de Mezerville, Nonhlanhla Khumalo, Ardeshir Bayat   +6 more
doaj   +1 more source

Chitosan-G-Glycidyl Methacrylate/Au Nanocomposites Promote Accelerated Skin Wound Healing

Pharmaceutics, 2022
Herein, we report the synthesis of Au nanoparticles (AuNPs) in chitosan (CTS) solution by chemically reducing HAuCl4. CTS was further functionalized with glycidyl methacrylate (chitosan-g-glycidyl methacrylate/AuNP, CTS-g-GMA/AuNP) to improve the ...
Héctor A. López-Muñoz, Mauricio Lopez-Romero, Moises A. Franco-Molina, Alejandro Manzano-Ramirez, Cristina Velasquillo, Beatriz Liliana España-Sanchez, Ana Laura Martinez-Hernandez, Hayde Vergara-Castañeda, Astrid Giraldo-Betancur, Sarai Favela, Rogelio Rodriguez-Rodriguez, Juan Carlos Mixteco, Juan Carlos Tapia-Picazo, Diana G. Zarate-Triviño, Evgeny Prokhorov, Gabriel Luna-Barcenas   +15 more
doaj   +1 more source

Revolutionizing transdermal drug delivery evaluation: the evolution from traditional models to skin organoids and the integration of artificial intelligence

Frontiers in Pharmacology
This review examines the evolution of evaluation systems for transdermal drug delivery systems (TDDS) alongside recent advances in skin organoids (SkOs).
Xinqiang Mo, Xinqiang Mo, Mingshi Qiu, Mingshi Qiu, Ru Song, Ru Song, Ru Song, Ru Song, Zhenjie Wu, Zhenjie Wu, Chunyan Liu, Chunyan Liu, Linqi Su, Linqi Su, Haiyi Wang, Haiyi Wang, Haiyi Wang, Rui Xue, Rui Xue, Lu Yu, Maoyao Wang, Maoyao Wang, Maoyao Wang, Ziyang Zhu, Ziyang Zhu, Peng Wu, Peng Wu, Jian Liu, Jian Liu, Yibing Wang, Yibing Wang, Siyuan Yin, Siyuan Yin, Siyuan Yin   +33 more
doaj   +1 more source