Results 91 to 100 of about 500 (242)

Novel targeted therapies in chordoma: an update

Therapeutics and Clinical Risk Management, 2015
Salvatore Di Maio,1 Stephen Yip,2 Gmaan A Al Zhrani,3,4 Fahad E Alotaibi,3,4 Abdulrahman Al Turki,3,4 Esther Kong,2 Robert C Rostomily5 1Division of Neurosurgery, Jewish General Hospital, McGill University, Montreal, QC, 2Department of Pathology ...
Di Maio S, Yip S, Al Zhrani GA, Alotaibi FE, Al Turki A, Kong E, Rostomily R   +6 more
doaj  

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

The mini-pretemporal approach for skull base neoplasms: A technical note

Surgical Neurology International
Background: Type 1 clinoidal meningiomas (ClinMens) grow from the inferior part of the clinoid process and are closely associated with the internal carotid artery (ICA) and optic apparatus. Surgical challenges stem from the intimal relation with the vascular adventitia and perineurium.
Erickson, Peter, Galenas, Isabella, Hemmer, Sina, Casanova-Martinez, Daniel, Mura, Jorge, Martinez-Perez, Rafael   +5 more
openaire   +2 more sources

Advances in the Management of Skull Base Meningioma

, 2012
Meningioma is among the most common intracranial neoplasms of adulthood and may be the most common primary intracranial tumor. While many tumors are asymptomatic and remain so throughout life, meningiomas of the skull base will frequently cause visual or
Prem S. Subramanian
core  

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Anterior Skull Base Glomangioma-Induced Osteomalacia

Journal of Neurological Surgery Reports, 2017
Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms.
Malia S. Gresham, Steven Shen, Yi J. Zhang, Kelly Gallagher   +3 more
doaj   +1 more source

Expression study of receptor tyrosine kinase targets of Imatinib mesylate in skull base chordomas [PDF]

, 2007
Chordomas are rare neoplasms arising along the axial skeleton. Up to now, the most suitable therapeutic approach is based on a combination of surgical excision and radiotherapy. Chemotherapy in not applied due to its reported low efficacy.
N. Boari, C. Doglioni, M. Longoni, P. Mortini, F. Orzan, M. Stroppi, M. R. Terreni, P. Riva   +7 more
core   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Subfrontal approach for nasal⁃cranial communicans tumor resection with nasal endoscope: analysis of 12 cases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To explore the methods and effects of operation via subfrontal approach with nasal endoscope for removing nasal⁃cranial communicans tumor. Methods Clinical data of 12 patients who underwent operation for nasal⁃cranial communicans tumor via ...
Zhi⁃fa HUANG, Xin YAO, Yu⁃shan YANG, Bu⁃dong CHEN, Hong WANG, Xiao⁃guang TONG, Jin⁃ling ZHANG, Gang LIU   +7 more
doaj  

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source