Results 81 to 90 of about 29,222 (335)

Chondroid chordoma of the parapharyngeal space: A case report and review of literature

Acta Oto-Laryngologica Case Reports, 2020
Parapharyngeal space (PPS) tumors are a rare entity and account for less than 1% of all head and neck tumors. Although they exhibit a benign behavior, malignant neoplasms may arise from any of the structure contained in the space.
Nasser Waleed Alobida, Aseel O. Doubi, Mohammed Alswayyed, Dima Z. Jamjoom, Khalid Al-Qahtani   +4 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

International Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis, Amy Eisenberg, Garni Barkhoudarian, Chester Griffiths, Daniel F. Kelly   +4 more
doaj   +1 more source

Primary Non-Hodgkin's Malignant Lymphoma of the Sinonasal Tract [PDF]

, 2009
Primary non-Hodgkin’s lymphomas (NHL) of the sinonasal tract are rather uncommon entities. Morphologically and radiographically, sinonasal lymphomas are difficult to distinguish from other malignant neoplasms or non- neoplastic processes.
Bhagat, Sanjeev, Bist, SS, Gupta, Nitin, Singh, Rakesh Kumar, Varshney, Saurabh   +4 more
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Comparative gene expression profiling of ADAMs, MMPs, TIMPs, EMMPRIN, EGF-R and VEGFA in low grade meningioma [PDF]

, 2016
MMPs (matrix metalloproteinases), ADAMs (a disintegrin and metalloproteinase) and TIMPs (tissue inhibitors of metalloproteinases) are implicated in invasion and angiogenesis: both are tissue remodeling processes involving regulated proteolysis of the ...
Andrew J. Martin, Andrew King, Barresi, Barresi, Barresi, Bourboulia, Brew, Clark, Edwards, Geoffrey J. Pilkington, Gialeli, Hagemann, Hagemann, Harcharan K. Rooprai, Huw Jones, Kessenbrock, Kirches, Kodama, Lettau, Louis, Love, Murphy, Nagase, Nagashima, Nordqvist, Nuttall, Okada, Okuducu, Patel, Perry, Perry, Pistolesi, Qu, Richard P. Selway, Richard W. Gullan, Rocks, Rooprai, Roy, Saftig, Sarkar, Silveira Corrêa, Stojic, Toft-Hansen, Tsai, Usha D. Appadu, Van Meter, von Randow, Wang, Wernicke, Wildeboer   +49 more
core   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Trans-nasal endoscopic and intra-oral combined approach for odontogenic cysts [PDF]

, 2018
Maxillary cysts are a common finding in maxillofacial surgery, dentistry and otolaryngology. Treatment is surgical; a traditional approach includes Caldwell-Luc and other intra-oral approaches.
Albanese, M., Fusetti, S., Lanaro, L., Lonardi, F., Marchioni, D., Molteni, G., Nocini, P. F., Procacci, P.   +7 more
core   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Endoscopic endonasal transclival resection of a “pontine chordoma”: Technical case report

Interdisciplinary Neurosurgery, 2019
Clival chordomas represent very challenging neoplasms, due to their tendency to infiltrate bone, frequent recurrence, involvement of important neurovascular structures, and deep location. Lesions involving the brainstem remain difficult to access through
Weiqi Zhang, MD, Yue Bao, MD, Yong Wang, MD, Yibao Wang, MD   +3 more
doaj   +1 more source

Post-traumatic cutaneous meningioma. [PDF]

, 2004
Cutaneous meningiomas are extremely rare tumours and their diagnosis is difficult. We describe the case of a patient who developed a paranasal swelling after head trauma and associated fractures in the same region years before.
Borggreven, P.A., Graaf, F.H. de, Leemans, C.R., Valk, P. van der   +3 more
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