Results 41 to 50 of about 328,746 (185)
Advanced Science, EarlyView.An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang +7 more
wiley +1 more source
Skull metastasis in urothelial cell carcinoma of the bladder [PDF]
, 2015 Urothelial cell carcinoma of the urinary bladder with metastasis to the skull is extremely rare. We present a case of occipital bone metastasis arising from a previously verified bladder urothelial carcinoma.
Liu, Jung-Tung +3 more
core +1 more source
Advanced Science, EarlyView.A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li +13 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe +8 more
wiley +1 more source
Bronchogenic Adenosquamous Cell Carcinoma with Metastasis to Skull: a Case Report [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2010 Introduction: Pulmonary Adenosquamous carcinoma is an uncommon histological variety of bronchogenic carcinoma, and has histologic areas differentiated as both squamous cell carcinoma and adenocarcinoma and has clinical behavior more like that of ...
Ghasem Janbabai +3 more
doaj +1 more source
Radiation Oncology, 2019 Background The aim of this study is to evaluate the prognostic value of grading MRI–detected skull-base invasion in nasopharyngeal carcinoma (NPC) with skull-base invasion after intensity-modulated radiotherapy (IMRT).
Yanru Feng +3 more
doaj +1 more source
North American Delphi Consensus Study on Sinonasal Malignancy Survivorship Care
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Survival for patients with sinonasal cancers has improved over the past decades, but there are no dedicated survivorship guidelines for this cohort. Objective To understand experts’ priorities and perspectives on key survivorship tenets (surveillance, second tumor screening, toxicity, and symptom management).
Matheus Sewastjanow‐Silva +18 more
wiley +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Olfactory neuroblastoma (ONB) exhibits variable recurrence patterns, with significant late recurrences occurring years after treatment. We investigated cutoff periods to define late recurrence and identified predictors that distinguish patients at risk of late recurrence from those considered cured.
Alexandria Harris +23 more
wiley +1 more source
99mTc-SPECT in the diagnosis of skull base metastasis
, 1997 Objective: To evaluate the role of bone SPECT in diagnosing metastasis to the skull base in cancer patients. Background: Skull base metastasis often causes characteristic clinical syndromes.
Sillevis Smitt, P. A.E. +5 more
core +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are rare aggressive malignancies with no established prognostic markers. Because features of POU2F3+ small cell lung carcinomas have been identified in both tumors, we evaluated immunostaining for POU2F3, a tuft cell transcription factor, and ...
Nikolina Dioufa +6 more
wiley +1 more source