Results 31 to 40 of about 14,247 (264)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The multifurcating skyline plot [PDF]

open access: yesVirus Evolution, 2018
Abstract A variety of methods based on coalescent theory have been developed to infer demographic history from gene sequences sampled from natural populations. The ‘skyline plot’ and related approaches are commonly employed as flexible prior distributions for phylogenetic trees in the Bayesian analysis of pathogen gene sequences.
Hoscheit, Patrick, Pybus, Oliver G.
openaire   +6 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

IMPROVED SKYLINE QUERY RETRIEVAL USING PARTICLE SWARM OPTIMIZATION BASED SWEEP LINE OPERATOR OVER REAL TIME DATASETS [PDF]

open access: yesICTACT Journal on Soft Computing, 2020
In this paper initially clusters the search area’s slopes, i.e. it is shaped into settings according to its behavior in the search area, both past and present.
A Sairam, Seenuvasan Arumugam
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Метод та програмний засіб формування Skyline-вибірок з багатовимірних даних

open access: yesAdaptivni Sistemi Avtomatičnogo Upravlinnâ
Метою даної роботи є вирішення проблем CoD та високої складності інтеграції існуючих рішень для формування Парето-фронтів шляхом розробки та впровадження методу та спеціалізованого програмного засобу формування Skyline-вибірок.
В. Кривоносюк   +1 more
doaj   +1 more source

Stochastic skyline operator [PDF]

open access: yes2011 IEEE 27th International Conference on Data Engineering, 2011
In many applications involving the multiple criteria optimal decision making, users may often want to make a personal trade-off among all optimal solutions. As a key feature, the skyline in a multi-dimensional space provides the minimum set of candidates for such purposes by removing all points not preferred by any (monotonic) utility/scoring functions;
Xuemin Lin 0001   +3 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Feedback-Driven Pattern Matching in Time Series Data

open access: yesIEEE Access
While motif discovery methods have come a long way over the years, they generally match occurrences based on the similar shape of the whole subsequence.
M. Van Onsem   +4 more
doaj   +1 more source

Application of Parallel Reaction Monitoring in 15N Labeled Samples for Quantification

open access: yesFrontiers in Plant Science, 2022
Accurate relative quantification is critical in proteomic studies. The incorporation of stable isotope 15N to plant-expressed proteins in vivo is a powerful tool for accurate quantification with a major advantage of reducing preparative and analytical ...
Andres V. Reyes   +6 more
doaj   +1 more source

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