Results 41 to 50 of about 92,772 (328)

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Horseshoe-based Bayesian nonparametric estimation of effective population size trajectories

, 2019
Phylodynamics is an area of population genetics that uses genetic sequence data to estimate past population dynamics. Modern state-of-the-art Bayesian nonparametric methods for recovering population size trajectories of unknown form use either change ...
Carpenter B., Easton N.A., Felsenstein J., Holmes C.E., Murray I., Neal R., Palacios J.A., R Core Team, Watanabe S.   +8 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Efficient Computation of Subspace Skyline over Categorical Domains

, 2017
Platforms such as AirBnB, Zillow, Yelp, and related sites have transformed the way we search for accommodation, restaurants, etc. The underlying datasets in such applications have numerous attributes that are mostly Boolean or Categorical.
Asudeh, Abolfazl, Das, Gautam, Koudas, Nick, Rahman, Md Farhadur   +3 more
core   +1 more source

Probabilistic contextual skylines [PDF]

2010 IEEE 26th International Conference on Data Engineering (ICDE 2010), 2010
The skyline query returns the most interesting tuples according to a set of explicitly defined preferences among attribute values. This work relaxes this requirement, and allows users to pose meaningful skyline queries without stating their choices. To compensate for missing knowledge, we first determine a set of uncertain preferences based on user ...
Dimitris Sacharidis, Anastasios Arvanitis, Timos K. Sellis   +2 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Skyline queries over incomplete multidimensional database [PDF]

, 2011
In recent years, there has been much focus on skyline queries that incorporate and provide more flexible query operators that return data items which are dominating other data items in all attributes (dimensions).Several techniques for skyline have been ...
Alwan, Ali A., Ibrahim, Hamidah, Sidi, Fatimah, Udzir, Nur Izura   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Метод та програмний засіб формування Skyline-вибірок з багатовимірних даних

Adaptivni Sistemi Avtomatičnogo Upravlinnâ
Метою даної роботи є вирішення проблем CoD та високої складності інтеграції існуючих рішень для формування Парето-фронтів шляхом розробки та впровадження методу та спеціалізованого програмного засобу формування Skyline-вибірок.
В. Кривоносюк, І. Стеценко   +1 more
doaj   +1 more source