Results 51 to 60 of about 2,699,597 (146)
, 2020 As life expectancy increases, the prevalence of osteoporosis is increasing. In addition to vitamin D which is well established to have an association with osteoporosis, B vitamins, such as thiamine, folate (vitamin B9), and cobalamin (vitamin B12), could
In-Bo Han +8 more
core +1 more source
Transcriptomic Insights Into the Immune Repertoire of an Antarctic Sponge
Ecology and Evolution, Volume 15, Issue 12, December 2025.Antarctic marine sponges are essential components of the benthic fauna, playing a crucial role in structuring this ecosystem through their own biological activities and their symbiotic relationships with diverse microorganisms. Yet, the transcriptional repertoire and the immune responses associated with interactions with microorganisms in this unique ...
Leslie K. Daille +3 more
wiley +1 more source
Hormone Research in Paediatrics, 2018 Objectives: Thiamine responsive megaloblastic anemia syndrome (TRMA) is characterized by the clinical triad of megaloblastic anemia, non- immune diabetes mellitus and sensorineural deafness. It is a very rare autosomal recessive disease with an increased frequency in consanguineous marriages and isolated communities.
Špehar Uroić, Anita +4 more
openaire +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Association of rs970740 with SLC19A2 cg1658605, cg0483076 and cg09671955 levels.
, 2014 p-values were adjusted for age, sex, batch, chip and cell type composition.In the F5L-families study, the rs970740 was not genotyped but substituted by the proxy rs2420371 that is in complete association (r2 = 1) with it.Association of rs970740 with ...
Pierre-Emmanuel Morange (161602) +10 more
core +1 more source
Medical Journal of Australia, Volume 223, Issue 9, Page 484-491, November 2025.Abstract Introduction Monogenic diabetes accounts for 2–5% of diabetes. Although its identification has substantial therapeutic implications, more than 80% of affected individuals are undiagnosed or misdiagnosed as having type 1 or 2 diabetes. This consensus statement reviews genetic testing for monogenic diabetes in adults and provides evidence‐based ...
Sunita MC De Sousa +10 more
wiley +1 more source
Structure‐based discovery of thiamine uptake inhibitors
British Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel +2 more
wiley +1 more source
Food Biomacromolecules, Volume 2, Issue 3, Page 271-287, September 2025.The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar +5 more
wiley +1 more source
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
Advanced Science, Volume 12, Issue 29, August 7, 2025.In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source
Association(1) of SLC19A2 CpG sites with ACVn (MARTHA) and APCR (F5L-families) phenotypes.
, 2014 (1) Association is expressed as % change in phenotype (95% Confidence Interval) for every 0.1 unit increase in methylation β-value.(2) Analysis were adjusted for age, sex, batch, chip and cell type composition.Association(1) of SLC19A2 CpG sites with ...
Pierre-Emmanuel Morange (161602) +10 more
core +1 more source