Results 51 to 60 of about 563,023 (137)

Vaginal candida infection is associated with host molecular signatures of neutrophil activation in the adjacent ectocervical mucosa in Kenyan sex workers

American Journal of Reproductive Immunology, Volume 91, Issue 2, February 2024.
Abstract Problem Overgrowth of candida species in the human vaginal mucosa causes inflammation, which could render the mucosal barrier more susceptible to HIV infection. Here, we investigated whether this condition also affects the ectocervical mucosa, a potential site of HIV entry, in women at high risk of HIV infection.
Tyra Hasselrot, Mathias Franzén Boger, Vilde Kaldhusdal, Alexandra Åhlberg, Kenneth Omollo, Julie Lajoie, Joshua Kimani, Annelie Tjernlund, Keith R. Fowke, Paulo Czarnewski, Kristina Broliden   +10 more
wiley   +1 more source

Incidence, Phenotypes, and Genotypes of Neonatal Diabetes: A 16‐Year Experience. The Rare Genetic Etiologies of Neonatal Diabetes Are Common in Sudan

Pediatric Diabetes, Volume 2024, Issue 1, 2024.
Neonatal diabetes (ND) is a rare subtype of diabetes occurring in the first 6 months of life. High incidence has been reported among populations with high rates of consanguineous marriage. However, there is paucity of reported data from sub‐Saharan African countries.
Samar S. Hassan, Salwa A. Musa, Elisa De Franco, Russel Donis Frew, Omer O. Babiker, Ghassan F. Mohamadsalih, Areej A. Ibrahim, Samar Abu Samra, Mohamed A. Abdullah, Reem Al Khalifah   +9 more
wiley   +1 more source

Thiamine-responsive megaloblastic anaemia syndrome: Long-term follow-up and mutation analysis of seven families

, 2006
Aim: Thiamine-responsive megaloblastic anaemia syndrome (TRMA) is the association of diabetes mellitus, anaemia and deafness, due to mutations in SLC19A2, encoding a thiamine transporter protein.
Ricketts, Christopher, Ricketts, CJ, Wales, JK, Ariyawansa, I, Minton, JA, Lo, IF, Barrett, TG, Barrett, Timothy; id_orcid, Samuel, J   +8 more
core   +1 more source

Recovered insulin production after thiamine administration in permanent neonatal diabetes mellitus with a novel solute carrier family 19 member 2 (SLC19A2) mutation

Journal of Diabetes, 2017
AbstractBackgroundSolute carrier family 19 member 2 (SLC19A2) gene deficiency is one of the causes of permanent neonatal diabetes mellitus (PNDM) and can be effectively managed by thiamine supplementation. Herein we report on a male patient with a novel SLC19A2 mutation and summarize the clinical characteristics of patients with SLC19A2 deficiency ...
Chengjun Sun, Zhou Pei, Miaoying Zhang, Bijun Sun, Lin Yang, Zhuhui Zhao, Ruoqian Cheng, Feihong Luo   +7 more
openaire   +1 more source

Association of rs970740 with SLC19A2 cg1658605, cg0483076 and cg09671955 levels.

, 2014
p-values were adjusted for age, sex, batch, chip and cell type composition.In the F5L-families study, the rs970740 was not genotyped but substituted by the proxy rs2420371 that is in complete association (r2 = 1) with it.Association of rs970740 with ...
Pierre-Emmanuel Morange (161602), Martin Ladouceur (144366), David-Alexandre Trégouët (133741), Nora Zwingerman (635735), Jessica Dennis (635734), Marine Germain (161547), Tara A. Paton (635737), Ares Rocanin-Arjo (635736), France Gagnon (73555), Vinh Truong (207097), Dylan Aïssi (635733)   +10 more
core   +1 more source

Association⁽¹⁾ of SLC19A2 CpG sites with ACVn (MARTHA) and APCR (F5L-families) phenotypes.

, 2014
(1) Association is expressed as % change in phenotype (95% Confidence Interval) for every 0.1 unit increase in methylation β-value.(2) Analysis were adjusted for age, sex, batch, chip and cell type composition.Association(1) of SLC19A2 CpG sites with ...
Pierre-Emmanuel Morange (161602), Martin Ladouceur (144366), David-Alexandre Trégouët (133741), Nora Zwingerman (635735), Jessica Dennis (635734), Marine Germain (161547), Tara A. Paton (635737), Ares Rocanin-Arjo (635736), France Gagnon (73555), Vinh Truong (207097), Dylan Aïssi (635733)   +10 more
core   +1 more source

Recurrent Stroke in a Child with TRMA Syndrome and SLC19A2 Gene Mutation.

Iranian journal of child neurology
Here we report a 5-month-old boy with thiamine Responsive Megaloblastic Anemia syndrome (TRMA syndrome) with several attacks of stroke, admitted to Mofid Children's Hospital, Tehran, Iran, in 2016. In addition to the cardinal clinical manifestations of the syndrome, other manifestations comprise thiamine-responsive megaloblastic anemia, diabetes ...
Parvaneh, Karimzadeh, Toktam, Moosavian, Hamidreza, Moosavian   +2 more
openaire   +1 more source

Effect of chronic exposure of pancreatic acinar 266-6 cells to NNK on activity of SLC19A2 and SLC19A3 promoters.

, 2013
Full-length SLC19A2 (A) and SLC19A3 (B) promoters in pGL3-Basic were transfected into 266-6 cells were exposed to 3 µM NNK for 24 h followed by determination of luciferase activity.
Veedamali S. Subramanian (452244), Padmanabhan Srinivasan (481324), Hamid M. Said (385809)   +2 more
core   +1 more source

Semantically Driven Mutation in Genetic Programming [PDF]

, 2008
Using semantic analysis, we present a technique known as semantically driven mutation which can explicitly detect and apply behavioural changes caused by the syntactic changes in programs that result from the mutation operation. Using semantically driven
Beadle, Lawrence, Colin G. Johnson, Johnson, Colin G., Lawrence Beadle   +3 more
core   +1 more source

Evolution strategies with q-Gaussian mutation for dynamic optimization problems [PDF]

, 2010
This article is posted here with permmission from IEEE - Copyright @ 2010 IEEEEvolution strategies with q-Gaussian mutation, which allows the self-adaptation of the mutation distribution shape, is proposed for dynamic optimization problems in this paper.
Yang, S, Tinos, Renato, Tinos, R, null Shengxiang Yang, Renato Tino, Yang, Shengxiang   +5 more
core   +1 more source