Results 161 to 170 of about 2,410 (172)
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Sodium-glucose cotransporter Sglt1 (Slc5a1) is present in various murine organs : sex-related expression in kidneys

2015
Diabetes mellitus affects ~400 million people worldwide. Novel antidiabetic drugs have been developed aiming to lower blood glucose by inhibiting the activity of sodium-D-glucose cotransporter 1 (SGLT1 in humans/Sglt1 in rodents) in the intestine and kidney.
Karaica, Dean   +3 more
openaire   +3 more sources

Species differences in the expression of sodium-D-glucose cotransporter 1 (SGLT1/SLC5A1), a potential therapeutic target in diabetes

2016
Cellular uptake and metabolism of glucose (G) serves as an important energy source. In mammals, SGLT1 (humans)/Sglt1 (rodents) mediates an almost complete absorption of G in small intestine (SI) and a limited (3-15%) reabsorption of G in kidneys (K). Novel antidiabetic drugs were recently developed aiming to lower blood G by inhibiting SGLT1 in SI and ...
Vrhovac Madunić, Ivana   +4 more
openaire   +2 more sources

Ekspresija prijenosnika natrija i glukoze Sglt1 (Slc5a1) u organima miševa

2015
In mice, sodium-glucose cotransporter (mSglt1/Slc5a1) absorbs and reabsorbs the glucose in the brush-border membrane of small intestinal enterocytes and renal proximal tubules, respectively. Due to unknown localization of mSglt1 in other organs/tissues, mSglt1 expression was determined comparing wild type (Sglt1+/+) and Sglt1 knockout mice (Sglt1 ...
openaire   +2 more sources

A Case of Congenital Glucose Galactose Malabsorption With a New Mutation in the SLC5A1 Gene

Journal of Pediatric Genetics, 2022
Hasan Akduman   +2 more
exaly  

Novel Mutation in the SLC5A1 Gene Causing... : JPGN Reports

JPGN Reports, 2023
Amanda C Fifi, Liz Febo-Rodriguez
exaly  

Congenital Glucose–Galactose Malabsorption: A Novel Deletion Within the SLC5A1 Gene

European Journal of Pediatrics, 2013
Stephanie Van Biervliet, Bart L Loeys
exaly  

Drosophila SLC5A11 Mediates Hunger by Regulating K+ Channel Activity

Current Biology, 2016
Bernardo Rudy, Seonil Kim, Monica Dus
exaly  

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