Results 221 to 230 of about 125,761 (305)

Integrating Patient-Centric Clinical Pharmacology and MID3 to Advance Biologic Development in Immune-Mediated Inflammatory Diseases. [PDF]

Clin Pharmacol Ther
Ait-Oudhia S, Zhang L, Pisal DS, Cicali B.   +3 more
europepmc   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Stigma, discrimination-related events, and determinants among adult people living with systemic lupus erythematosus (SLE): Systematic review and indicator-level meta-analysis. [PDF]

Lupus
Abdulazeem HM, Bellakhal S, Abida R, Soliman S.   +3 more
europepmc   +1 more source

Early haematologic response to anifrolumab in SLE: results from the European multicentre EFFORT-SLE study. [PDF]

Rheumatology (Oxford)
Gasparotto M, Bettiol A, De Marchi G, Biancalana E, Duro G, Fagni F, Horisberger A, Mitrović J, Nano A, Wawrzycka-Adamczyk K, Reisch M, Salamon L, Schett G, Šenolt L, Silvestri E, Thiel J, Tomietto P, Wójcik K, Závada J, Quartuccio L, Emmi G.   +20 more
europepmc   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

Rheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu, Ming Zheng, Danny Arias, Andreina M. Paulino, Aisha Niaz, James Devlin, Valentin Marian   +6 more
wiley   +1 more source

Integrated Mendelian Randomization and Single-Cell Transcriptomics Reveal T Cell Immune Mechanisms in Systemic Lupus Erythematosus-Bladder Cancer Comorbidity. [PDF]

Life (Basel)
Zhang D, Ren H, Bai Y, Han P.
europepmc   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Nursing students' perceptions and experiences of student-lecturer evaluation as a strategy for improving teaching and learning at the University of Namibia. [PDF]

Curationis
Stanislaus RK, Ashipala DO, Amadhila J.
europepmc   +1 more source

Granzyme K: A new frontier in systemic lupus erythematosus

Rheumatology &Autoimmunity, EarlyView.
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen, Yunjing Pu, Peihui Yang, Qinghuan Zhu, Haojun Long, Danqi Deng   +5 more
wiley   +1 more source

Mitochondrial DNA in systemic lupus erythematosus: pathogenic mechanisms, clinical biomarkers, and precision therapeutic strategies. [PDF]

Front Immunol
Huang F, Sun K, Diao L, Lu K, Fan Y, Xie G.   +5 more
europepmc   +1 more source