Results 91 to 100 of about 2,261 (196)
Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients
Movement Disorders, EarlyView.Abstract Background Hereditary ataxias are genetically diverse, yet up to 75% remain undiagnosed due to technological and financial barriers. The GGC repeat expansion in ZFHX3, responsible for spinocerebellar ataxia type 4 (SCA4), has only been described in individuals of Northern Europeandescent.
Paula Saffie‐Awad +22 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Excessive daytime sleepiness (EDS) is a disabling symptom of Lewy body disorders (LBD). The hypothalamus is a key sleep–wake regulator and is involved in Lewy pathology, but its contribution to EDS in LBD remains unclear. Objectives To use diffusion‐weighted magnetic resonance imaging (MRI) to detect hypothalamic microstructure and ...
Jesse S. Cohen +8 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Objective To compare iron deposition in the substantia nigra (SN) as measured with quantitative susceptibility mapping (QSM) on antemortem magnetic resonance imaging (MRI) between individuals with and without Lewy‐related pathology at autopsy. Methods We performed a retrospective cohort study including 54 participants who underwent autopsy and
Patricia Diaz‐Galvan +28 more
wiley +1 more source
Characteristic Effects of Anti-dementia Drugs on Rat Sleep Patterns
Journal of Pharmacological Sciences, 2009 The present study was undertaken to clarify the effects of anti-dementia drugs on sleep pattern in rats. Electrodes were chronically implanted into the frontal cortex and the dorsal neck muscle of rats for the electroencephalogram (EEG) and ...
Takayuki Ishida, Chiaki Kamei
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Molecular Nutrition &Food Research, EarlyView.This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina +15 more
wiley +1 more source
The Primary Function of Rem Sleep [PDF]
SSRN Electronic Journal, 2006 In this paper, the physiological features associated with the different stages of REM sleep and with what information processing researchers have called “effort” and “arousal” are compared. It is suggested that tonic REM sleep and effort involve an increase in the metabolism of cerebral glycogen, and phasic REM sleep and arousal involve the transfer of
openaire +3 more sources
ChemistryOpen, EarlyView.This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid +14 more
wiley +1 more source
SoftwareXRapid eye movement (REM) sleep plays a crucial role in brain functions such as memory consolidation and mood regulation. Alterations in REM sleep and REM sleep behaviour disorders are early biomarkers of neurodegenerative disorders. The microstructure of
Kiran K G Ravindran, Derk-Jan Dijk
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Neurobiology of Disease, 2018 The lateral hypothalamus contains neurons producing orexins that promote wakefulness and suppress REM sleep as well as neurons producing melanin-concentrating hormone (MCH) that likely promote REM sleep.
Fumito Naganuma +5 more
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