Results 91 to 100 of about 49,955 (299)

Automated scoring of pre-REM sleep in mice with deep learning

Scientific Reports, 2021
Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies ...
Niklas Grieger, Justus T. C. Schwabedal, Stefanie Wendel, Yvonne Ritze, Stephan Bialonski   +4 more
doaj   +1 more source

Restless REM Sleep Impedes Overnight Amygdala Adaptation [PDF]

, 2019
Animal studies show that insufficient silencing of the locus coeruleus (LC) during REM sleep impairs sleep-related brain plasticity. Restless REM sleep, a characteristic of several psychiatric disorders, likely reflects insufficient LC silencing.
Stoffers, Diederick, Stoffers, D., Van Someren, Eus J.W., Van Someren, E.J.W., Schalkwijk, F., Ramautar, J.R., Ramautar, Jennifer R., Wassing, Rick, Lakbila-Kamal, Oti, Schalkwijk, F.; id_orcid, van Someren, Eus J. W., Lakbila-Kamal, O., Wassing, R.   +12 more
core   +1 more source

Sleep‐trackers in the wild: A faceted taxonomy for information and interaction design

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Consumer‐grade sleep‐tracking technologies (CSTs) have brought sleep into everyday data practices, reframing it from a clinical concern into a site of personal optimization and reflection. Yet existing taxonomies of sleep‐tracking often medicalize users and overlook the complexity of sleep‐tracking technologies. This paper presents SleepTax, a
Sanonda Datta Gupta, Jaime Snyder, John S. Seberger   +2 more
wiley   +1 more source

The relationship between sleep disturbance and depression

, 2006
This paper focuses on several aspects of the relationship between sleep and depression, with particular attention to objective factors and subjective perceptions.
Mayers, Andrew G., David S. Baldwin, Baldwin, David S., Andrew G. Mayers, Mayers, A.G., Baldwin, D.S.   +5 more
core   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Evolutionary Origin of Distinct NREM and REM Sleep

Frontiers in Psychology, 2020
Sleep is mandatory in most animals that have the nervous system and is universally observed in model organisms ranging from the nematodes, zebrafish, to mammals.
Risa Yamazaki, Hirofumi Toda, Paul-Antoine Libourel, Yu Hayashi, Yu Hayashi, Kaspar E. Vogt, Takeshi Sakurai, Takeshi Sakurai   +7 more
doaj   +1 more source

A medullary hub for controlling REM sleep and pontine waves

Nature Communications, 2023
Rapid-eye-movement (REM) sleep is a distinct behavioral state associated with vivid dreaming and memory processing. Phasic bursts of electrical activity, measurable as spike-like pontine (P)-waves, are a hallmark of REM sleep implicated in memory ...
Amanda L. Schott, Justin Baik, Shinjae Chung, Franz Weber   +3 more
doaj   +1 more source

Inter‐rater reliability and clinical utility of the BASED score in infantile epileptic spasms syndrome

Epileptic Disorders, EarlyView.
Abstract Objective Hypsarrhythmia is the classical EEG pattern of children with infantile epileptic spasms syndrome (IESS). Multifocal spikes, slow waves of large amplitude, and chaoticity are its main characteristics, but these lack clear definitions, and the interrater reliability (IRR) is poor.
T. P. Cramer, B. Johnsen, V. S. Hansen, E. Qerama, T. S. Engedal   +4 more
wiley   +1 more source

Blood pressure dipping during REM and non-REM sleep in patients with moderate to severe obstructive sleep apnea

Scientific Reports, 2021
A limited number of papers have addressed the association between non-dipping-blood pressure (BP) obstructive sleep apnea (OSA), and no study has assessed BP-dipping during rapid eye movement (REM) and non-REM sleep in OSA patients.
Ahmed S. BaHammam, Mana Alshahrani, Salih A. Aleissi, Awad H. Olaish, Mohammed H. Alhassoon, Afnan Shukr   +5 more
doaj   +1 more source

Selective REM sleep deprivation in narcolepsy

, 2011
Narcolepsy is characterized by excessive daytime sleepiness and rapid eye movement (REM) sleep abnormalities, including cataplexy. The aim of this study was to assess REM sleep pressure and homeostasis in narcolepsy.
MANH HOANG VU, Vu, Manh Hoang, Mathis, Johannes, Bassetti, Claudio L, CLAUDIO L. BASSETTI, CHRISTOPH HURNI, JOHANNES MATHIS, CORINNE ROTH, Roth, Corinne, Hurni, Christoph   +9 more
core   +1 more source