Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. [PDF]
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons of the lateral sector of the posterior hypothalamus and zona incerta.
Benedetto, Luciana+8 more
core +3 more sources
Discovery of key whole-brain transitions and dynamics during human wakefulness and non-REM sleep
The modern understanding of sleep is based on the classification of sleep into stages defined by their electroencephalography (EEG) signatures, but the underlying brain dynamics remain unclear. Here we aimed to move significantly beyond the current state-
A. Stevner+15 more
semanticscholar +1 more source
Altered sleep and EEG power in the P301S Tau transgenic mouse model [PDF]
OBJECTIVE: Sleep disturbances are prevalent in human tauopathies yet despite the importance of sleep, little is known about its relationship with tau pathology.
Holth, Jerrah K+4 more
core +2 more sources
REM sleep in acutely traumatized individuals and interventions for the secondary prevention of post-traumatic stress disorder [PDF]
Increasing evidence supports a close link between REM sleep and the consolidation of emotionally toned memories such as traumatic experiences. In order to investigate the role of sleep for the development of symptoms related to traumatic experiences ...
Bublitz, Jan Christoph+6 more
core +1 more source
Dynamic modulation of theta-gamma coupling during REM sleep.
Theta phase modulates gamma amplitude in hippocampal networks during spatial navigation and rapid eye movement (REM) sleep. This cross-frequency coupling has been linked to working memory and spatial memory consolidation, however, its spatial and ...
M. Bandarabadi+6 more
semanticscholar +1 more source
Evaluating the evidence surrounding pontine cholinergic involvement in REM sleep generation
Rapid eye movement (REM) sleep - characterized by vivid dreaming, motor paralysis, and heightened neural activity - is one of the fundamental states of the mammalian central nervous system.
Kevin P Grace, Richard L Horner
doaj +1 more source
Daytime REM sleep affects emotional experience but not decision choices in moral dilemmas [PDF]
Moral decision-making depends on the interaction between automatic emotional responses and rational cognitive control. A natural emotional regulator state seems to be sleep, in particular rapid eye movement (REM) sleep.
Cellini, Nicola+3 more
core +2 more sources
REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories
A brain pathway for active forgetting Sleep affects memories via several mechanisms. Izawa et al. identified a possible new pathway in the brain: REM sleep–active hypothalamic melanin-concentrating hormone (MCH)–producing neurons, which, among others ...
Shuntaro Izawa+12 more
semanticscholar +1 more source
Objective To investigate the clinical characteristics and influencing factors of insomnia in perimenopausal women based on polysomnography (PSG). Methods A total of 52 perimenopausal women admitted to our psychological clinic due to insomnia were ...
ZHAO Yuan, CHEN Qingqiu, JIANG Chenggang
doaj +1 more source
Are there sleep-specific phenotypes in patients with chronic fatigue syndrome? A cross-sectional polysomnography analysis [PDF]
Objectives: Despite sleep disturbances being a central complaint in patients with chronic fatigue syndrome (CFS), evidence of objective sleep abnormalities from over 30 studies is inconsistent.
Deary, Vincent+3 more
core +1 more source