Results 51 to 60 of about 690,481 (322)

A predictive propensity measure to enter REM sleep

open access: yesFrontiers in Neuroscience
IntroductionDuring sleep periods, most mammals alternate multiple times between rapid-eye-movement (REM) sleep and non-REM (NREM) sleep. A common theory proposes that these transitions are governed by an “hourglass-like” homeostatic need to enter REM ...
Alexander G. Ginsberg   +6 more
doaj   +1 more source

Effects Of 4-thiazolidinone Derivatives Les-2658 And Les-1205 On Sleep - Wakefulness Cycle In Kindled Rats [PDF]

open access: yes, 2017
The research is dedicated to in-depth study of neurotrophic and antiepileptic properties of original potential anticonvulsant agents from 4-thiazolidinones – LES-2658 (5-(3-nitro-benzylidene)-2-(thiazol-2-ylimino)-thiazolidin-4-one) and LES-1205 ([2,4 ...
Lesyk, R. (Roman)   +2 more
core   +2 more sources

Regulation of REM and Non-REM Sleep by Periaqueductal GABAergic Neurons

open access: yesNature Communications, 2018
Mammalian sleep consists of distinct rapid eye movement (REM) and non-REM (NREM) states. The midbrain region ventrolateral periaqueductal gray (vlPAG) is known to be important for gating REM sleep, but the underlying neuronal mechanism is not well ...
F. Weber   +6 more
semanticscholar   +1 more source

Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. [PDF]

open access: yesPLoS ONE, 2013
GABA is the major inhibitory neurotransmitter in the mammalian central nervous system that has been strongly implicated in the regulation of sleep. GABA transporter subtype 1 (GAT1) constructs high affinity reuptake sites for GABA and regulates GABAergic
Xin-Hong Xu   +6 more
doaj   +1 more source

Reply to Grace: Role of cholinergic neurons in rapid eye movement (REM) sleep control [PDF]

open access: yes, 2017
We thank Grace (1) for the opportunity to discuss the role of cholinergic neurons in rapid eye movement (REM) sleep further. Grace suggests that optogenetic activation of a population of neurons does not necessarily demonstrate their role in the ...
Brown, Emery Neal, Van Dort, Christa Joy
core   +1 more source

REM sleep homeostasis in the absence of REM sleep: Effects of antidepressants

open access: yesNeuropharmacology, 2016
Most antidepressants suppress rapid eye movement (REM) sleep, which is thought to be important to brain function, yet the resulting REM sleep restriction is well tolerated. This study investigated the impact of antidepressants with different mechanisms of action, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCA)
Dale M. Edgar   +6 more
openaire   +4 more sources

Neurobehavioral Associations with NREM and REM Sleep Architecture in Children with Autism Spectrum Disorder

open access: yesChildren, 2022
Objective: Insomnia and daytime behavioral problems are common issues in pediatric autism spectrum disorder (ASD), yet specific underlying relationships with NonRapid Eye Movement sleep (NREM) and Rapid Eye Movement (REM) sleep architecture are ...
Jennifer Nguyen   +4 more
doaj   +1 more source

REM sleep’s unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Sleep disturbances are common in stress-related disorders but the nature of these sleep disturbances and how they relate to changes in the stress hormone corticosterone and changes in gene expression remained unknown.
M. Nollet   +10 more
semanticscholar   +1 more source

Melanin-concentrating hormone (MCH): a new sleep factor?

open access: yesFrontiers in Neurology, 2011
Neurons that utilize the neuropeptide melanin-concentrating hormone (MCH) as a neuromodulator are mainly located in the lateral hypothalamus and the incerto-hypothalamic area, and have widespread projections throughout the brain.
Pablo eTorterolo   +2 more
doaj   +1 more source

A Fast-Slow Analysis of the Dynamics of REM Sleep

open access: yes, 2012
Waking and sleep states are regulated by the coordinated activity of a number of neuronal population in the brainstem and hypothalamus whose synaptic interactions compose a sleep-wake regulatory network.
Booth, Victoria, Diniz Behn, Cecilia G.
core   +1 more source

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