Results 61 to 70 of about 49,955 (299)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

A rare case of REM sleep-related bradyarrhythmia syndrome with concomitant severe hypertension: a case report and a review of literature

Acta Medica Lituanica, 2018
Introduction. Rapid eye movement (REM) sleep-related bradyarrhythmia syndrome is characterized by pathological asystoles during the REM sleep phase. It is a rare rhythm disorder, being reported only few times in the literature.
Gabrielius Jakutis, Vytautas Juknevičius, Juratė Barysienė, Dalia Matačiūnienė, Birutė Petrauskienė, Žaneta Petrulionienė, Aleksandras Laucevičius   +6 more
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Gastrodin Improves Cognitive Dysfunction in REM Sleep-Deprived Rats by Regulating TLR4/NF-κB and Wnt/β-Catenin Signaling Pathways

Brain Sciences, 2023
Gastrodin is the active ingredient in Gastrodia elata. Our previous studies demonstrated that gastrodin ameliorated cerebral ischemia–reperfusion and hypoperfusion injury and improved cognitive deficit in Alzheimer’s disease.
Bo Liu, Fei Li, Yunyan Xu, Qin Wu, Jingshan Shi   +4 more
doaj   +1 more source

Effects of sleep fragmentation on the arousability to resistive loading in NREM and REM sleep in normal men

, 2006
STUDY OBJECTIVE: In healthy subjects, arousability to inspiratory resistive loading is greater during rapid eye movement (REM) sleep compared with non-REM (NREM) sleep but is poorest in REM sleep in patients with sleep apnea.
Corinne Roth, Matthias Gugger, Gugger, Matthias, Bassetti, Claudio L, Mathis, Johannes, Claudio L. Bassetti, Johannes Mathis, Zavodny, Jeannette, Jeannette Zavodny, Neil J. Douglas, Douglas, Neil J, Roth, Corinne   +11 more
core   +1 more source

REM Sleep Behaviour Disorder, a narrative review from a technological perspective. [PDF]

, 2023
STUDY OBJECTIVES Isolated REM sleep behaviour disorder (iRBD) is a parasomnia characterized by dream enactment. It represents a prodromal state of alpha-synucleinopathies, like Parkinson's disease.
Bassetti, C, Wulf, M, Schäfer, C, Nef, T, Gnarra, Oriella   +4 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

ScoreREM: A user-friendly Matlab-GUI for rapid eye movement (REM) sleep microstructure (Phasic/Tonic) annotation and quantification

SoftwareX
Rapid eye movement (REM) sleep plays a crucial role in brain functions such as memory consolidation and mood regulation. Alterations in REM sleep and REM sleep behaviour disorders are early biomarkers of neurodegenerative disorders. The microstructure of
Kiran K G Ravindran, Derk-Jan Dijk
doaj   +1 more source

Characteristic Effects of Anti-dementia Drugs on Rat Sleep Patterns

Journal of Pharmacological Sciences, 2009
The present study was undertaken to clarify the effects of anti-dementia drugs on sleep pattern in rats. Electrodes were chronically implanted into the frontal cortex and the dorsal neck muscle of rats for the electroencephalogram (EEG) and ...
Takayuki Ishida, Chiaki Kamei
doaj   +1 more source

A Child with REM Sleep Disturbance [PDF]

Journal of Clinical Sleep Medicine, 2010
An 8-year-old patient presented with history of snoring. He also had complaints of an upset stomach at night and talking during sleep. The child reportedly banged his head or rocked his body when going to sleep. He woke more than twice per night on average, and her had trouble falling back asleep. Epworth Sleepiness Scale score was 3.
Amarbir, Mattewal, Lata, Casturi, Shyam, Subramanian   +2 more
openaire   +2 more sources