Results 51 to 60 of about 331,232 (268)
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Eye movement patterns correlate with overt emotional behaviours in rapid eye movement sleep
Scientific Reports, 2022 Growing evidence suggests that sleep plays a key role in regulating emotions. Rapid eye movements (REMs) in REM sleep could be associated with dreams emotions, but supporting evidence is indirect.
Jean-Baptiste Maranci +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Military Medical Research, 2019 Background Sleep disorders frequently occur in posttraumatic stress disorder (PTSD) patients. Chronic insomnia is a common feature of and criteria for the diagnosis of PTSD. Another sleep disorder, obstructive sleep apnea (OSA), also occurs frequently in
Barry J. Krakow +3 more
doaj +1 more source
MULTI-PHACET: multidimensional clinical phenotyping of hospitalised acute COPD exacerbations
ERJ Open Research, 2021 Background The generic term “exacerbation” does not reflect the heterogeneity of acute exacerbations of COPD (AECOPD). We utilised a novel algorithmic strategy to profile exacerbation phenotypes based on underlying aetiologies.
Martin I. MacDonald +8 more
doaj +1 more source
Facilitating 1.5T MR‐Linac adoption: Workflow strategies and practical tips
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Background MR‐guided radiotherapy (MRgRT) offers new opportunities but also introduces workflow complexities requiring dedicated optimization. Implementing magnetic resonance linear accelerator (MR‐Linac) technology comes with challenges such as prolonged treatment times and workflow integration issues.
Madeline Michel +9 more
wiley +1 more source
Scientific Reports, 2022 Mental health conditions confer considerable global disease burden in young adults, who are also the highest demographic to work shifts, and of whom 20% meet criteria for a sleep disorder.
Amy C. Reynolds +12 more
doaj +1 more source
Classifying sleep states using persistent homology and Markov chain: a Pilot Study [PDF]
arXiv, 2020 Obstructive sleep Apnea (OSA) is a form of sleep disordered breathing characterized by frequent episodes of upper airway collapse during sleep. Pediatric OSA occurs in 1-5% of children and can related to other serious health conditions such as high blood pressure, behavioral issues, or altered growth.
arxiv
Classification of sleep stages from EEG, EOG and EMG signals by SSNet [PDF]
arXiv, 2023 Classification of sleep stages plays an essential role in diagnosing sleep-related diseases including Sleep Disorder Breathing (SDB) disease. In this study, we propose an end-to-end deep learning architecture, named SSNet, which comprises of two deep learning networks based on Convolutional Neuron Networks (CNN) and Long Short Term Memory (LSTM).
arxiv