Results 61 to 70 of about 2,778,168 (382)
A Fast-Slow Analysis of the Dynamics of REM Sleep
, 2012 Waking and sleep states are regulated by the coordinated activity of a number of neuronal population in the brainstem and hypothalamus whose synaptic interactions compose a sleep-wake regulatory network.
Booth, Victoria, Diniz Behn, Cecilia G.
core +1 more source
Sleep patterns of Japanese preschool children and their parents: implications for co-sleeping [PDF]
, 2013 Aim The aim of this study was to investigate the direct relationship of sleep schedule and sleep quality variables between healthy preschool children and their parents, focusing on the influence of the difference in bedtime between each other.
Iwata, O, Iwata, S, Matsuishi, T
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Treating restless legs syndrome in the context of sleep disordered breathing comorbidity
European Respiratory Review, 2019 Obstructive sleep apnoea (OSA) and restless legs syndrome (RLS) are two of the most prevalent sleep disorders and can coexist within the same patient. Nonetheless, the recognition of RLS among OSA patients has important clinical implications, since RLS ...
Sofía Romero-Peralta +4 more
doaj +1 more source
Is Sleep-Related Eating Disorder (SRED) a NREM Parasomnia or a Heterogenous Disease?
Clinical and Translational Neuroscience, 2023 Sleep-related eating disorder (SRED) is a relatively rare but probably underestimated disorder, where affected patients exhibit nocturnal eating episodes with impaired consciousness and subsequent amnesia. SRED has originally been classified as NREM (non-
Nico Zobrist +2 more
doaj +1 more source
Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study [PDF]
, 2015 © 2015 Asian Pacific Society of Respirology. Background and objective The management of chronic refractory breathlessness is one of the indications for regular low-dose (≤30 mg/24 h) oral sustained release morphine.
Abernethy, Amy P. +6 more
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
, 2019 Sleep is a very important part of the day for everyone. There are many reasons why people should be striving to get the sleep they need. However, many people are skipping out on an hour or two of the recommended time.
Buscher, Henry
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FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source