Results 31 to 40 of about 859,657 (394)
Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents : an in vitro study [PDF]
Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness, especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep.
A Alonso+72 more
core +7 more sources
The effects of mild–moderate partial sleep deprivation on affective and cognitive functioning were evaluated in a naturalistic home environment, mimicking short sleep typically caused by demands from work or society.
I. Saksvik-Lehouillier+10 more
semanticscholar +1 more source
The effect of nitric oxide on spatial learning and memory impairment following rapid eye movement (REM) sleep deprivation in rats [PDF]
Background and Aim: Sleep deprivation causes impairment in learning and memory. Several studies have shown the positive effect of nitric oxide on learning and memory processes.
Mahdi Bodagh, Majid Taati
doaj +2 more sources
Chronic sleep loss is a potent catabolic stressor, increasing the risk of metabolic dysfunction and loss of muscle mass and function. To provide mechanistic insight into these clinical outcomes, we sought to determine if acute sleep deprivation blunts ...
S. Lamon+9 more
semanticscholar +1 more source
Depriving Mice of Sleep also Deprives of Food [PDF]
Both sleep-wake behavior and circadian rhythms are tightly coupled to energy metabolism and food intake. Altered feeding times in mice are known to entrain clock gene rhythms in the brain and liver, and sleep-deprived humans tend to eat more and gain weight. Previous observations in mice showing that sleep deprivation (SD) changes clock gene expression
Nina Đukanović+5 more
openaire +5 more sources
Acute and chronic sleep deprivation in residents: Cognition and stress biomarkers
Insufficient sleep affects circadian hormonal profiles and inflammatory markers and may modulate attention, executive functioning and decision‐making. Medical professionals and specifically resident physicians, who are involved in long‐term nightshift ...
Shoham Choshen-Hillel+6 more
semanticscholar +1 more source
Decline of long-range temporal correlations in the human brain during sustained wakefulness [PDF]
Sleep is crucial for daytime functioning, cognitive performance and general well-being. These aspects of daily life are known to be impaired after extended wake, yet, the underlying neuronal correlates have been difficult to identify.
Achermann, Peter+3 more
core +3 more sources
The regulation of sleep and the response to sleep deprivation rely on multiple biochemical pathways. A critical connection is the link between sleep and metabolism.
Matthew S. Thimgan+4 more
doaj +1 more source
Translational changes induced by acute sleep deprivation uncovered by TRAP-Seq
Sleep deprivation is a global health problem adversely affecting health as well as causing decrements in learning and performance. Sleep deprivation induces significant changes in gene transcription in many brain regions, with the hippocampus ...
Lisa C. Lyons+4 more
doaj +1 more source
β-Amyloid accumulation in the human brain after one night of sleep deprivation
Significance There has been an emerging interest in sleep and its association with β-amyloid burden as a risk factor for Alzheimer’s disease. Despite the evidence that acute sleep deprivation elevates β-amyloid levels in mouse interstitial fluid and in ...
E. Shokri-Kojori+16 more
semanticscholar +1 more source