Results 71 to 80 of about 907,577 (363)
Brain Sciences, 2023 Gastrodin is the active ingredient in Gastrodia elata. Our previous studies demonstrated that gastrodin ameliorated cerebral ischemia–reperfusion and hypoperfusion injury and improved cognitive deficit in Alzheimer’s disease.
Bo Liu +4 more
doaj +1 more source
Sleep deprivation differentially affects subcomponents of cognitive control
Sleep, 2019 STUDY OBJECTIVES Although sleep deprivation has long been known to negatively affect cognitive performance, the exact mechanisms through which it acts and what cognitive domains are affected most is still disputed.
Anikó Kusztor +5 more
semanticscholar +1 more source
Effects of Sleep Deprivation on the Tryptophan Metabolism
International Journal of Tryptophan Research, 2020 Sleep has a regulatory role in maintaining metabolic homeostasis and cellular functions. Inadequate sleep time and sleep disorders have become more prevalent in the modern lifestyle.
Abid R Bhat +4 more
semanticscholar +1 more source
Associations of Sleep and Shift Work with Osteoarthritis Risk
Arthritis Care &Research, Accepted Article.Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik +5 more
wiley +1 more source
The Effects of Sleep Deprivation on Pain
Pain Research and Management, 2004 Chronic pain syndromes are associated with alterations in sleep continuity and sleep architecture. One perspective of this relationship, which has not received much attention to date, is that disturbances of sleep affect pain. To fathom this direction of
Bernd Kundermann +3 more
doaj +1 more source
Decline of long-range temporal correlations in the human brain during sustained wakefulness [PDF]
, 2017 Sleep is crucial for daytime functioning, cognitive performance and general well-being. These aspects of daily life are known to be impaired after extended wake, yet, the underlying neuronal correlates have been difficult to identify.
Achermann, Peter +3 more
core +3 more sources
Sleepiness as motivation: a potential mechanism for how sleep deprivation affects behavior
Sleep, 2019 Study Objectives To determine how sleepiness and sleep deprivation drive the motivation to engage in different behaviors. Methods We studied the sleepiness of 123 participants who had been randomized to sleep deprivation or normal sleep, and their ...
John Axelsson +5 more
semanticscholar +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Arthritis Care &Research, Accepted Article.Background Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined: 1) associations between economic insecurities and PROs; 2) the impact of screening and addressing economic insecurities during ...
Jay Patel +8 more
wiley +1 more source
Nicotinic Mitigation of Neuroinflammation and Oxidative Stress After Chronic Sleep Deprivation
Frontiers in Immunology, 2019 Sleep deprivation negatively influences all aspects of health. Oxidative stress and inflammatory responses induced by sleep deprivation participate in its adverse effects but the regulatory mechanisms to counteract them remain poorly understood.
Rong Xue +5 more
semanticscholar +1 more source
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source