Results 51 to 60 of about 3,871,182 (341)

Sleep Stage Classification by a Combination of Actigraphic and Heart Rate Signals

Journal of Low Power Electronics and Applications, 2017
Although heart rate variability and actigraphic data have been used for sleep-wake or sleep stage classifications, there are few studies on the combined use of them. Recent wearable sensors, however, equip both pulse wave and actigraphic sensors.
Emi Yuda, Yutaka Yoshida, Ryujiro Sasanabe, Haruhito Tanaka, Toshiaki Shiomi, Junichiro Hayano   +5 more
doaj   +1 more source

Relationship between sleep quality and quality of life in patients with bipolar disorder [PDF]

Sleep Science, 2020
Objective: Sleep disorder is one of the most classic symptoms of patients with bipolar I disorder (BID), which affects their quality of life (QOL).
Farshid Shamsaei, Samira Yadollahifar, Amir Sadeghi   +2 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Systematic Review of Sleep Disturbances and Circadian Sleep Desynchronization in Autism Spectrum Disorder: Toward an Integrative Model of a Self-Reinforcing Loop

Frontiers in Psychiatry, 2019
Background: A compelling number of studies, conducted in both children and adults, have reported an association between sleep disturbances/circadian sleep alterations and autism spectrum disorder (ASD); however, the data are sparse and the nature of this
C. Carmassi, L. Palagini, D. Caruso, I. Masci, L. Nobili, A. Vita, L. Dell’Osso   +6 more
semanticscholar   +1 more source

Circadian clock dysregulation: a potential mechanism of depression in obstructive sleep apnea patients

Translational Psychiatry
Obstructive sleep apnea (OSA) is characterized by co-occurrence with affective disorders. Our study aims to investigate the association of circadian clock gene expressions, and the presence and severity of depressive symptoms in OSA patients.
Agata Gabryelska, Szymon Turkiewicz, Piotr Kaczmarski, Adrian Gajewski, Piotr Białasiewicz, Dominik Strzelecki, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo, Kilian Hett, Amy Cooper, Amy E. Brown, Jessica Iregui, Manus J. Donahue, M. Erik Landman, Italo Biaggioni, Margaret Bradbury, Cynthia Wong, David Stamler, Daniel O. Claassen   +11 more
wiley   +1 more source

Assessment of continuous positive airway pressure effect on the circadian clock signaling pathway in obstructive sleep apnea patients

Scientific Reports
Obstructive sleep apnea (OSA) is associated with circadian rhythm dysregulation plausibly through affecting clock genes. The study’s purpose was to investigate the effect of one-night continuous positive airway pressure treatment (CPAP treatment) on ...
Agata Gabryelska, Szymon Turkiewicz, Adrian Gajewski, Julia Jaromirska, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

Vestibular Evoked Myogenic Potentials Are Abnormal in Idiopathic REM Sleep Behavior Disorder

Frontiers in Neurology, 2018
Objectives: To investigate brainstem function in idiopathic REM sleep Behavior Disorder (iRBD), a condition occurring as a result of a derangement of connections within brainstem structures, with a battery of Vestibular Evoked Myogenic Potentials (VEMPs),
Edoardo Rosario de Natale, Francesca Ginatempo, Ilaria Laccu, Michela Figorilli, Andrea Manca, Beniamina Mercante, Monica Puligheddu, Franca Deriu   +7 more
doaj   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Exploring differences in signaling pathways of the circadian clock and neuromodulators in obstructive sleep apnea

Scientific Reports
Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurring upper airway obstructions, leading to disrupted sleep and systemic complications. The complexity of OSA suggests intricate interactions between neuromodulators and circadian
Szymon Turkiewicz, Marcin Sochal, Marta Ditmer, Adrian Gajewski, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Agata Gabryelska   +7 more
doaj   +1 more source