Results 51 to 60 of about 579,778 (352)

Circadian clock dysregulation: a potential mechanism of depression in obstructive sleep apnea patients

Translational Psychiatry
Obstructive sleep apnea (OSA) is characterized by co-occurrence with affective disorders. Our study aims to investigate the association of circadian clock gene expressions, and the presence and severity of depressive symptoms in OSA patients.
Agata Gabryelska, Szymon Turkiewicz, Piotr Kaczmarski, Adrian Gajewski, Piotr Białasiewicz, Dominik Strzelecki, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

Bidirectional Relationship Between Sleep Disturbances and Parkinson's Disease

Frontiers in Neurology, 2022
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease (AD). Both diseases share common clinical and pathological features: the gradual progression of neurological and psychiatric symptoms caused by ...
Eiko N. Minakawa, Eiko N. Minakawa, Eiko N. Minakawa, Eiko N. Minakawa   +3 more
doaj   +1 more source

CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad, Arnau Puig‐Davi, Iñigo Ruíz‐Barrio, Javier Pagonabarraga, Anna Vázquez‐Oliver, Andrea Horta‐Barba, Jaime Kulisevsky, Saül Martínez‐Horta   +7 more
wiley   +1 more source

Diversity and noise effects in a model of homeostatic regulation of the sleep-wake cycle [PDF]

, 2012
Recent advances in sleep neurobiology have allowed development of physiologically based mathematical models of sleep regulation that account for the neuronal dynamics responsible for the regulation of sleep-wake cycles and allow detailed examination of ...
Braun, Hans A., Hernández-García, Emilio, Patriarca, Marco, Postnova, Svetlana, Toral, Raúl   +4 more
core   +4 more sources

Assessment of continuous positive airway pressure effect on the circadian clock signaling pathway in obstructive sleep apnea patients

Scientific Reports
Obstructive sleep apnea (OSA) is associated with circadian rhythm dysregulation plausibly through affecting clock genes. The study’s purpose was to investigate the effect of one-night continuous positive airway pressure treatment (CPAP treatment) on ...
Agata Gabryelska, Szymon Turkiewicz, Adrian Gajewski, Julia Jaromirska, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

Vestibular Evoked Myogenic Potentials Are Abnormal in Idiopathic REM Sleep Behavior Disorder

Frontiers in Neurology, 2018
Objectives: To investigate brainstem function in idiopathic REM sleep Behavior Disorder (iRBD), a condition occurring as a result of a derangement of connections within brainstem structures, with a battery of Vestibular Evoked Myogenic Potentials (VEMPs),
Edoardo Rosario de Natale, Francesca Ginatempo, Ilaria Laccu, Michela Figorilli, Andrea Manca, Beniamina Mercante, Monica Puligheddu, Franca Deriu   +7 more
doaj   +1 more source

Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova, Lang Liu, Ziv Gan‐Or, Konstantin Senkevich   +3 more
wiley   +1 more source

The Association of Sleep Disorder, Obesity Status, and Diabetes Mellitus among US Adults—The NHANES 2009-2010 Survey Results [PDF]

, 2013
To examine the association between sleep disorders, obesity status, and the risk of diabetes in adults, a total of 3668 individuals aged 40+ years fromtheNHANES 2009-2010 withoutmissing information on sleep-related questions,measurements related to ...
Faught, Brent E., Hay, John, Liu, Jian
core   +3 more sources

Exploring differences in signaling pathways of the circadian clock and neuromodulators in obstructive sleep apnea

Scientific Reports
Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurring upper airway obstructions, leading to disrupted sleep and systemic complications. The complexity of OSA suggests intricate interactions between neuromodulators and circadian
Szymon Turkiewicz, Marcin Sochal, Marta Ditmer, Adrian Gajewski, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Agata Gabryelska   +7 more
doaj   +1 more source

Brief Psychoeducational and Cognitive Therapy for Nightmare Disorder (BPCT-ND)

Sleep Science
In adults, nightmare disorder is related to sleep deprivation, drug consumption or abuse, or other comorbid sleep disorders such as insomnia or insufficient sleep syndrome.
Horacio Balam Álvarez-García, Ulises Jiménez-Correa   +1 more
doaj   +1 more source