ABSTRACT Problems with initiating and maintaining sleep are among the most common health complaints, with prevalence rates exceeding 50% depending on the survey. Preventing the progression to chronic insomnia may reduce public healthcare costs and prevent secondary illnesses.
Maren‐Jo Kater +3 more
wiley +1 more source
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads +8 more
wiley +1 more source
The integrative role of melatonin in psychiatric disorders: A systematic review of evidence from circadian biology, lifestyle medicine, and psychoneuroimmunology. [PDF]
Le HBC +4 more
europepmc +1 more source
ABSTRACT Recent studies have shown that acoustic stimulation, a common neuromodulation technique, can enhance slow‐wave activity (SWA), which is associated with immune, autonomic nervous system activity and cognitive health benefits. Despite some disagreement, many studies suggest that maximising tone‐evoked SWA depends on the timing of the acoustic ...
Mohamad Forouzanfar +4 more
wiley +1 more source
A randomized controlled trial examining the impact of diversified nursing interventions on the circadian rhythm of sedated critically ill patients. [PDF]
Zhang M +6 more
europepmc +1 more source
Effects of Agomelatine on Sleep Across Populations: A Systematic Review and Meta‐Analysis
ABSTRACT Agomelatine, a melatoninergic antidepressant, is often prescribed to improve sleep disturbance, though meta‐analytic evidence is currently lacking. This systematic review and meta‐analysis assessed its efficacy and tolerability in sleep outcomes compared to placebo.
Anastasios Stefanou +7 more
wiley +1 more source
The feasibility of salivary melatonin in assessing perioperative circadian rhythm in surgical patients: study protocol for a multicentre prospective study in China. [PDF]
Chen B +17 more
europepmc +1 more source
Sleep Deprivation in Mice: Looking Beyond the Slow Wave Rebound
ABSTRACT Sleep is a fundamental process supporting the dynamic regulation of neural function. Emerging methods have proposed that the aperiodic components of brain signals (such as the spectral slope, spectral intercept, and spectral knee), in addition to entropy‐based measures, offer robust empirical markers of neural states.
Tárek Zoltán Magyar +2 more
wiley +1 more source
Circadian rhythm profiles derived from accelerometer measures of the sleep-wake cycle in two cohort studies. [PDF]
Vidil S +8 more
europepmc +1 more source

