Sick and tired: how molecular regulators of human sleep schedules and duration impact immune function. [PDF]
Why do we need to sleep? What regulates when we sleep? And what dictates the number of hours we require? These are often viewed as three separate biological questions.
Chong, SY Christin+3 more
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Bright Light Therapy in Parkinson's Disease: An Overview of the Background and Evidence
Sleep disorders are common in Parkinson's disease (PD) and seem to be strongly associated with depression. It has been suggested that sleep disorders as well as depression are caused by a disturbed circadian rhythm.
Sonja Rutten+5 more
doaj +1 more source
Solving the mystery of human sleep schedules one mutation at a time. [PDF]
Sleep behavior remains one of the most enigmatic areas of life. The unanswered questions range from "why do we sleep?" to "how we can improve sleep in today's society?" Identification of mutations responsible for altered circadian regulation of human ...
Fu, Ying-Hui+2 more
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Circadian rhythms and sleep in bipolar disorder [PDF]
Murray G, Harvey A. Circadian rhythms and sleep in bipolar disorder. Bipolar Disord 2010: 12: 459–472. © 2010 The Authors. Journal compilation © 2010 John Wiley & Sons A/S.Objective: Biological rhythm pathways are highlighted in a number of etiological models of bipolar disorder, and the management of circadian instability appears in consensus ...
Murray, Greg, Harvey, Allison
openaire +4 more sources
Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions [PDF]
A workshop was held at the National Institute for Diabetes and Digestive and Kidney Diseases with a focus on the impact of sleep and circadian disruption on energy balance and diabetes.
Arble, Deanna M+28 more
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Acute Sleep-Wake Cycle Shift Results in Community Alteration of Human Gut Microbiome
Disturbances of sleep and the underlying circadian rhythm are related to many human diseases, such as obesity, diabetes, cardiovascular disorders, and cognitive impairments. Dysbiosis of the gut microbiome has also been reported to be associated with the
Zhi Liu+13 more
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Time-Restricted Feeding Improves Circadian Dysfunction as well as Motor Symptoms in the Q175 Mouse Model of Huntington's Disease. [PDF]
Huntington's disease (HD) patients suffer from a progressive neurodegeneration that results in cognitive, psychiatric, cardiovascular, and motor dysfunction.
Colwell, Christopher S+5 more
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Sex Differences in Insomnia and Circadian Rhythm Disorders: A Systematic Review
Insomnia and circadian rhythm disorders are increasingly common in modern society and lead to significant challenges for people’s health and well-being. Some studies suggests that men and women differ in neurohormonal secretion, biological processes, and
Evelina Pajėdienė+4 more
doaj +1 more source
Circadian period and the timing of melatonin onset in men and women: Predictors of sleep during the weekend and in the laboratory [PDF]
Sleep complaints and irregular sleep patterns, such as curtailed sleep during workdays and longer and later sleep during weekends, are common. It is often implied that differences in circadian period and in entrained phase contribute to these patterns ...
Archer, SN+7 more
core +2 more sources
Circadian rest-activity rhythms predict cognitive function in early Parkinson's disease independently of sleep [PDF]
BACKGROUND: Cognitive impairment is a common and debilitating symptom of Parkinson's disease (PD), and its etiology is likely multifactorial. One candidate mechanism is circadian disruption. Although there is evidence of circadian abnormalities in PD, no
Cronin-Golomb, Alice+4 more
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