Bright Light Therapy in Parkinson's Disease: An Overview of the Background and Evidence
Sleep disorders are common in Parkinson's disease (PD) and seem to be strongly associated with depression. It has been suggested that sleep disorders as well as depression are caused by a disturbed circadian rhythm.
Sonja Rutten +5 more
doaj +1 more source
Queixas de insônia e sonolência excessiva são comuns na investigação dos distúrbios respiratórios do sono; os transtornos do sono relacionados ao ritmo circadiano talvez sejam as causas mais freqüentemente esquecidas no diagnóstico diferencial destes ...
Denis Martinez +2 more
doaj +1 more source
COVID-19 breakthrough infections and sleep disorders: A population-based propensity matched analysis
Objectives: Examine risks for breakthrough COVID-19 infections in vaccinated patients with selected sleep disorders. Methods: Real-time search and analysis using the TriNetX platform to evaluate risk of COVID-19 breakthrough infections (BTI) for patients
Mantavya Punj +4 more
doaj +1 more source
Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis [PDF]
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological ...
A Agusti +79 more
core +2 more sources
Acute Sleep-Wake Cycle Shift Results in Community Alteration of Human Gut Microbiome
Disturbances of sleep and the underlying circadian rhythm are related to many human diseases, such as obesity, diabetes, cardiovascular disorders, and cognitive impairments. Dysbiosis of the gut microbiome has also been reported to be associated with the
Zhi Liu +13 more
doaj +1 more source
Assaying locomotor activity to study circadian rhythms and sleep parameters in Drosophila. [PDF]
Most life forms exhibit daily rhythms in cellular, physiological and behavioral phenomena that are driven by endogenous circadian (≡24 hr) pacemakers or clocks. Malfunctions in the human circadian system are associated with numerous diseases or disorders.
Chiu, Joanna C +4 more
core +3 more sources
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. [PDF]
In humans, the connection between sleep and mood has long been recognized, although direct molecular evidence is lacking. We identified two rare variants in the circadian clock gene PERIOD3 (PER3-P415A/H417R) in humans with familial advanced sleep phase ...
Fu, Ying-Hui +15 more
core +1 more source
Sex Differences in Insomnia and Circadian Rhythm Disorders: A Systematic Review
Insomnia and circadian rhythm disorders are increasingly common in modern society and lead to significant challenges for people’s health and well-being. Some studies suggests that men and women differ in neurohormonal secretion, biological processes, and
Evelina Pajėdienė +4 more
doaj +1 more source

