Results 61 to 70 of about 1,833,255 (278)
BackgroundAggressive behavior in patients with schizophrenia poses significant challenges to community management. Although disruption of circadian rhythm is a recognized risk factor, the underlying mechanisms related to sleep disorders and social ...
Li-Juan Duan +12 more
doaj +1 more source
Considerable attention has been paid to individuals showing social maladjustment as well as withdrawal from social situations and activity, a state referred to as “Hikikomori” in Japanese.
Nana N. Takasu +2 more
doaj +1 more source
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
Bidirectional Relationship Between Circadian Rhythm and Frailty
Yu Pan,* Zhu Qing Feng,* Yan Yuan,* Gui Ming Hu, Yi Jiang, Jiang Chuan Dong Department of Geriatrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of China*This authors Contributed ...
Pan Y +5 more
doaj
Fibromyalgia Syndrome and Chronotype: Late Chronotypes Are More Affected [PDF]
Sleep has strong links to the symptomology of fibromyalgia syndrome (FMS), a diffuse musculoskeletal pain disorder. Information about the involvement of the circadian clock is, however, sparse. In this study, 1548 individuals with FMS completed an online
Roenneberg, Till +7 more
core +1 more source
Migraine and Sleep Disorders: A Narrative Review [PDF]
Headaches and sleep problems are burdensome in daily life. They can co-occur and aggravate each other. The prevalence of sleep disorders is high in chronic headache and migraine patients, suggesting a close clinical relationship between these conditions.
이원우, 주민경
core +1 more source
Objectives To elucidate role of beta‐transducin repeat‐containing protein 2 (β‐TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. Methods The role of β‐TrCP2 in bone phenotypes was investigated using systemic β‐TrCP1KO and β‐TrCP2KO mice, along with myeloid‐specific conditional β‐TrCP2KO (β‐TrCP2ΔM) mice.
Woo Jung Kim +14 more
wiley +1 more source
Plasticity of the intrinsic period of the human circadian timing system. [PDF]
Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human circadian pacemaker under lighting intensities to which astronauts are typically exposed. Failure
Frank A J L Scheer +4 more
doaj +1 more source
Diurnal preference and sleep quality: same genes? A study of Young Adult twins [PDF]
The aims of this study were to examine the genetic and environmental influences on diurnal preference and sleep quality, the association between these phenotypes, the genetic and environmental influences on this association, and the magnitude of overlap ...
Eley, Thalia C. +19 more
core +1 more source
The hidden burden of sleep in adolescents with idiopathic generalized epilepsy
Abstract Background Idiopathic Generalized Epilepsies (IGEs) are electroclinical syndromes characterized by distinct seizure types, EEG patterns, and presumed polygenic inheritance. While seizure prognosis is often favorable, sleep disturbances, behavioral and emotional difficulties, and executive function impairment are common, especially during ...
Carlo Alberto Quaranta +8 more
wiley +1 more source

