Results 61 to 70 of about 63,213 (287)

Melatonin use in sleep disorders [PDF]

open access: yes, 1997
Melatonin is a widely publicized 'magical drug'. Claims of its use include regulation of sleep, circadian rhythm, mood, immune system and reproduction, anti-aging, protection against cancer, and treatment of AIDS. This article reviews the evidence of its
Chung, KF
core  

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

Importance of regular lifestyle with daytime bright light exposure on circadian rhythm sleep–wake disorders in pervasive developmental disorders

open access: yesJapanese Dental Science Review, 2011
Considerable attention has been paid to individuals showing social maladjustment as well as withdrawal from social situations and activity, a state referred to as “Hikikomori” in Japanese.
Nana N. Takasu   +2 more
doaj   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Bidirectional Relationship Between Circadian Rhythm and Frailty

open access: yesNature and Science of Sleep, 2023
Yu Pan,* Zhu Qing Feng,* Yan Yuan,* Gui Ming Hu, Yi Jiang, Jiang Chuan Dong Department of Geriatrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of China*This authors Contributed ...
Pan Y   +5 more
doaj  

Cognition in menopausal women

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Cognitive health in postmenopausal women is significantly affected by hormonal shifts, especially the drop in estrogen levels. This review explores the intricate relationship between menopause and cognitive functions across six domains: perception, attention, memory, language, executive functioning, and motor skills.
Suvarna Khadilkar   +3 more
wiley   +1 more source

Plasticity of the intrinsic period of the human circadian timing system. [PDF]

open access: yesPLoS ONE, 2007
Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human circadian pacemaker under lighting intensities to which astronauts are typically exposed. Failure
Frank A J L Scheer   +4 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

open access: yesInterdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu   +10 more
wiley   +1 more source

MicroRNA: A Key Player for the Interplay of Circadian Rhythm Abnormalities, Sleep Disorders and Neurodegenerative Diseases

open access: yesClocks & Sleep, 2020
Circadian rhythms are endogenous 24-h oscillators that regulate the sleep/wake cycles and the timing of biological systems to optimize physiology and behavior for the environmental day/night cycles.
Chisato Kinoshita   +3 more
doaj   +1 more source

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