Results 111 to 120 of about 158,325 (315)

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

open access: yesAdvanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari   +3 more
wiley   +1 more source

Sleep disturbances in Parkinson's disease patients and management options

open access: yes, 2011
Daniel O Claassen, Scott J KutscherDepartment of Neurology, Vanderbilt University, Nashville, TN, USAAbstract: Sleep disturbances are among the most common nonmotor complaints of patients with Parkinson's disease (PD), and can have a great impact
Kutscher SJ, Claassen DO
core  

A screening method for sleep disturbances at the end-of-life

open access: yes, 2020
Objective. To evaluate sleep disturbances and to verify the accuracy of three screening tests to detect them in patients at the end-of-life admitted in a hospital palliative care unit. Method.
Cruzado Rodríguez, Juan Antonio   +1 more
core   +1 more source

Sleep problems and sensory features in children with low-average cognitive abilities and autism spectrum disorder

open access: yesScientific Reports
Children with Autism Spectrum Disorder (ASD) often have more sleep disturbances than typically developing children. These sleep disturbances have been suggested to be associated with atypical sensory features in children with ASD.
Sumie Iwasaki   +7 more
doaj   +1 more source

Sleep disturbance in the elderly.

open access: yesNippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1990
Sleep structure is qualitatively and quantitatively changed by aging. The elderly usually go to bed in early evening and wake up in early morning, and they also take several naps in the day time. The polyphasic sleep is one of the typical sleep patterns found in the elderly.
openaire   +3 more sources

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

open access: yesAdvanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng   +7 more
wiley   +1 more source

Sleep problems in childhood: a longitudinal study of developmental change and association with behavioral problems

open access: yes, 2002
Objective: The objective of the study was to examine specificity, order of appearance, and developmental changes in the relationships between sleep problems and behavioral problems in children.
O'Connor, Thomas G., Gregory, Alice M.
core  

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

open access: yesAdvanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang   +6 more
wiley   +1 more source

Sleep in spousal Alzheimer caregivers: a longitudinal study with a focus on the effects of major patient transitions on sleep

open access: yes, 2012
Findings on sleep disturbances in family dementia caregivers are conflicting. We studied the longitudinal effects of dementia caregiving and major transitions in the caregiving situation on caregivers' sleep and the effect of moderating ...
Roepke, Susan K   +10 more
core   +1 more source

Sleep disturbances and nightmares in victims of sexual abuse with post-traumatic stress disorder: an analysis of abuse-related characteristics

open access: yesEuropean Journal of Psychotraumatology, 2019
Background: Sexual abuse victims often experience symptoms of post-traumatic stress disorder (PTSD), including sleep disturbances. Objective: To investigate whether or not characteristics of sexual abuse are associated with sleep disturbance, and to ...
Geneviève Belleville   +2 more
doaj   +1 more source

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