Results 121 to 130 of about 703,277 (252)

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Sleep and neuropsychological functioning in school aged children

, 2009
This thesis investigated the relationship between sleep disturbance and neuropsychological functioning in healthy, typically developing children and children with cystic fibrosis (CF). Three research questions were examined in this thesis.
Holley, Simone Lisa
core   +1 more source

Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson’s disease

npj Parkinson's Disease
Disrupted sleep has a profound adverse impact on lives of Parkinson’s disease (PD) patients and their caregivers. Sleep disturbances are exceedingly common in PD, with substantial heterogeneity in type, timing, and severity.
K. C. Summa, P. Jiang, P. González-Rodríguez, X. Huang, X. Lin, M. H. Vitaterna, Y. Dan, D. J. Surmeier, F. W. Turek   +8 more
doaj   +1 more source

Impact of Mild Traumatic Brain Injury on Sleep Patterns in Younger Individuals: A Systematic Review

Neurotrauma Reports
Concussions or mild traumatic brain injuries (mTBI) are a frequent outcome of contact sports, and adolescents and young adults face a disproportionately higher risk of repeated injury.
Sid Subramanian, Caitlin M. Carroll
doaj   +1 more source

The effect of donepezil on sleep and REM sleep EEG in patients with Alzheimer disease: A double-blind placebo-controlled study

, 2006
Study Objective: Examine the effects of donepezil on sleep and rapid eye movement (REM) sleep electroencephalogram (EEG) in patients with Alzheimer disease, using polysomnography, and the correlation between REM sleep EEG parameters and cognitive scores ...
Ferreira Bertolucci, Paulo Henrique [UNIFESP], Christian Guilleminault, Sergio Tufik, Guilleminault, Christian, Moraes, Walter André dos Santos [UNIFESP], Tufik, Sergio [UNIFESP], Walter André dos Santos Moraes, Ramos, Luiz Roberto [UNIFESP], Poyares, Dalva [UNIFESP], Paulo Henrique Ferreira Bertolucci, Dalva Rollemberg Poyares, Luiz Roberto Ramos   +11 more
core   +1 more source

Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory

Anatomical Sciences Education, EarlyView.
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson, Abbey Breckling, Danielle N. Edwards, Nicole Geske, Burhan Gharaibeh, Bobbie J. Leeper, Molly Ostwald, Mary Schilling, Bridgett Severt, Kelsey Stevens, J. P. Swigart, Jonathan J. Wisco, Melissa Zolnierz, Jeremy J. Grachan   +13 more
wiley   +1 more source

Economic evaluations of antiobesity medications: A systematic literature review

British Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković, Almir Fajkić, Andrea Katrin Faour, Mirna Momčilović, Petra Turčić, Andrej Belančić   +5 more
wiley   +1 more source

The influence of non-breathing-related sleep fragmentation on cognitive function in patients with cerebral small vessel disease

, 2019
Jihui Wang,1,* Xiaodong Chen,2,* Jinchi Liao,2 Li Zhou,3 Siyuan Liao,2 Yilong Shan,2 Zhengqi Lu,2 Jiong Tao1 1Department of Psychiatry, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, People’s Republic of China ...
Liao J, Zhou L, Tao J, Shan Y, Lu Z, Chen X, Liao S, Wang J   +7 more
core  

‘School is their whole world’: Teachers' perspectives on loneliness among children and adolescents from England and mainland China

British Educational Research Journal, EarlyView.
Abstract As front‐line observers and active participants in pupils' daily lives, teachers closely monitor pupils' social interactions, emotional states and behavioural changes. Their unique perspective enables them to detect problems in the social lives of their pupils that may not be immediately visible to peers, parents or mental health professionals.
Yixuan Zheng, Charlotte Bagnall, Caroline Bond, Elizabeth Birchinall, Pamela Qualter   +4 more
wiley   +1 more source

Digital Transformation on Green Operational Performance: Evidence From the E‐Waste Firm's Perspective

Business Strategy and the Environment, EarlyView.
ABSTRACT Digital transformation (DT) is increasingly recognised as essential for improving environmental performance in process‐intensive and hazardous sectors; however, the mechanisms by which digitalisation translates into green operational performance (GOP) and environmental accountability remain insufficiently investigated, particularly in ...
Amila Kasun Sampath Udage Kankanamge, Michael Odei Erdiaw‐Kwasie, Matthew Abunyewah   +2 more
wiley   +1 more source