Cognitive impairment in comorbid MDD and OSA: the dual effects of intermittent hypoxia and sleep fragmentation. [PDF]
Zhang J +7 more
europepmc +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
Beyond the Eye: Sleep Fragmentation, Autonomic Dysregulation, and Mitochondrial Dysfunction as a Common Biological Soil for Meibomian Gland Pathology. [PDF]
Lin YH, Chen JY, Chen CL.
europepmc +1 more source
Monitoring and assessment for obstructive sleep apnea
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu +6 more
wiley +1 more source
High-resolution sleep fragmentation assessment in narcolepsy type 1 and their non-narcoleptic siblings: a 5-s mini-epoch study. [PDF]
Follin LF +11 more
europepmc +1 more source
This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen +5 more
wiley +1 more source
Neuromodulation and Copper Chelation Reverse Sleep Fragmentation-Aggravated Myocardial Ischemia-Reperfusion Injury by Targeting NET-Induced Endothelial Cuproptosis. [PDF]
Shi P +10 more
europepmc +1 more source
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome. [PDF]
Taylor MA +8 more
europepmc +1 more source
Operating in perpetual motion? Coping with the dark side of global boundary spanning
Abstract Research Summary This paper explores how individuals experience and cope with the demands of global boundary spanning in multinational enterprises (MNEs). We foreground temporary colocation as a modality through which mobile global boundary spanners repeatedly traverse multiple boundaries, triggering intense demands with adverse consequences ...
Kieran M. Conroy +2 more
wiley +1 more source

