Results 191 to 200 of about 703,277 (252)

Sleep recovery alleviates impaired glucose tolerance induced by sleep fragmentation possibly through gut microbiota in mice. [PDF]

Sci Rep
Zhang J, Zhong L, Yi X, Yao X, Wen Y, Yang J, Li B, Gao S, Li M.   +8 more
europepmc   +1 more source

Longitudinal associations between sleepiness and sleep disturbances across pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Although sleep disturbances increase during pregnancy, sleepiness does not appear to follow a similar trajectory. Given that the relationship between sleep disturbances and sleepiness during pregnancy is understudied, we examined their associations to determine whether these relationships strengthen with advancing gestation.
Linda Aukia, Laura Perasto, Linnea Karlsson, Hasse Karlsson, E. Juulia Paavonen, Päivi Polo‐Kantola   +5 more
wiley   +1 more source

A pilot study on the effect of severe sleep fragmentation on aorta remodelling, neuroinflammation in a rat model. [PDF]

Sci Rep
Perek N, Guillot P, Mounichetty C, Dumas V, Maia S, Forest F, Roche F.   +6 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Chronic Sleep Fragmentation Differentially Affects Alzheimer's Disease Pathology in Male and Female APP^SAA Knock-in Mice. [PDF]

J Inflamm Res
Hawkins MR, Whitlock HR, Johnson CE, Macheda T, Cox MF, Lapid MG, Roberts KN, Hash HM, Drinkard EG, Sunderam S, O'Hara BF, Murphy MP, Duncan MJ, Bachstetter AD.   +13 more
europepmc   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Enduring non-rapid eye movement sleep fragmentation following methotrexate chemotherapy in cancer-naïve mice. [PDF]

Sleep
Boyd L, Berisha A, Gomez AM, Gibson EM, Borniger JC.   +4 more
europepmc   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

A Two-Hit Model of Executive Dysfunction: Simulated Galactic Cosmic Radiation Primes Latent Deficits Revealed by Sleep Fragmentation. [PDF]

Life (Basel)
Britten RA, Tamgue EN, Arriaga Alvarado P, Fesshaye AS, Sanford LD.   +4 more
europepmc   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source