Results 81 to 90 of about 703,277 (252)

Sleep Instabilities Assessed by Cardiopulmonary Coupling Analysis Increase During Childhood and Adolescence

Frontiers in Physiology, 2018
The electrocardiogram-based cardiopulmonary coupling (CPC) technique may be used to track sleep instabilities. With progressing age, maturational changes during childhood and adolescence affect sleep.
Dirk Cysarz, Maijana Linhard, Georg Seifert, Friedrich Edelhäuser   +3 more
doaj   +1 more source

Increased Disease Activity is Associated with Altered Sleep Architecture in an Experimental Model of Systemic Lupus Erythematosus

, 2010
Study Objectives: The aim of this study was to evaluate sleep patterns during the course of the disease in (NZB/NZW)F(1) mice, an experimental model of systemic lupus erythematosus (SLE).Design: Female mice were implanted with electrodes for chronic ...
S. Tufik, Sergio Tufik, Tufik, Sergio [UNIFESP], Palma, Beatriz Duarte [UNIFESP], B.D. Palma, Beatriz Duarte Palma   +5 more
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Editorial on the Special Issue “Obstructive Sleep Apnea (OSA)”

Life
Obstructive sleep apnea (OSA) is the most common form of sleep-disordered breathing and is characterized by recurrent episodes of complete or partial upper airway obstruction during sleep, resulting in oxygen desaturation, autonomic dysfunction and sleep
Konstantinos Chaidas
doaj   +1 more source

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Sleep is viewed as a fundamental restorative function of the brain, but its specific role in neural energy budget remains poorly understood. Sleep deprivation dampens brain energy metabolism and impairs cognitive functions.
Petit, Jean-Marie, Magistretti, Pierre J., Audrey, Nguyen, Parafita, Julia, Baud, Maxime O.   +4 more
core   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Sleep and cognitive problems in patients with attention-deficit hyperactivity disorder

Neuropsychiatric Disease and Treatment, 2014
Hae Kook Lee, Jong-Hyun Jeong, Na-Young Kim, Min-hyeon Park, Tae-Won Kim, Ho-Jun Seo, Hyun-Kook Lim, Seung-Chul Hong, Jin-Hee Han Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea Objectives: Attention ...
Lee HK, Jeong JH, Kim NY, Park MH, Kim TW, Seo HJ, Lim HK, Hong SC, Han JH   +8 more
doaj  

Sleep structure and autonomic nervous system state during four months of isolation in a space analogue mission

Frontiers in Human Neuroscience
IntroductionInsufficient or disturbed sleep impairs nocturnal physiological recovery and may negatively affect autonomic nervous system (ANS) regulation.
Martin Glos, Matthew Salanitro, Naima Laharnar, Artem Demin, Thomas Penzel, Ingo Fietze, Ingo Fietze   +6 more
doaj   +1 more source

Possible negative effects of snoring and increased sleep fragmentation on developmental status of preschool children

, 2014
Limited studies have investigated the effects of snoring although harmful neurocognitive effects of obstructive sleep apnea syndrome are relatively well known. The aim of the present study was to investigate the effects of snoring and fragmented sleep on
Koc, Derya, Yorbik, Ozgur, Mutlu, Caner, Mutluer, Tuba   +3 more
core   +1 more source

AI Powered Biobanks From Static Archives to Dynamic Discovery Engines

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin, Yutian Feng, Wenrui Ma, Yuxin Su, Li Min, Juan Liu   +5 more
wiley   +1 more source