Results 131 to 140 of about 22,100 (204)

Functional regression with intensively measured longitudinal outcomes: a new lens through data partitioning

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Modern longitudinal data from wearable devices consist of biological signals at high‐frequency time points. Distributed statistical methods have emerged as a powerful tool to overcome the computational burden of estimation and inference with large data, but methodology for distributed functional regression remains limited.
Cole Manschot, Emily C. Hector
wiley   +1 more source

An Orthogonal Way of Writing the Tubulin Code

open access: yesCytoskeleton, EarlyView.
ABSTRACT The Elongator complex has long been characterized for its role in tRNA modification and modulation of protein translation. Beyond these established functions, recent findings reveal an unexpected role for Elongator in directly interacting and tuning microtubule dynamics and properties, broadening its biological significance in eukaryotic cells.
Vicente Jose Planelles‐Herrero   +1 more
wiley   +1 more source

Global perspectives on the Sleep Condition Indicator for DSM-5 insomnia disorder: a COSMIN and STARD systematic review of psychometric and diagnostic performance. [PDF]

open access: yesBMC Med
Meng R   +14 more
europepmc   +1 more source

Pharmacokinetics, Tolerability, and Biomarker Profile of the Neurokinin 3 Receptor Antagonist Fezolinetant in Healthy Japanese Individuals: A 2‐Part, Randomized, Phase 1 Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This 2‐part, randomized, placebo‐controlled, double‐blind, Phase 1 study analyzed the pharmacokinetics, safety, and biomarker profile of fezolinetant in healthy Japanese individuals. Part 1: male participants received single doses of placebo or fezolinetant 15 or 60 mg.
Akira Koibuchi   +8 more
wiley   +1 more source

Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Obesity surgery (OS) results in substantial, albeit heterogeneous, long‐term improvements in weight and mental health, with unclear trajectories and their associations. This study examined multivariate trajectories of weight, psychopathology, and health‐related quality of life (HRQOL) after OS, and their prospective association with ...
Anja Hilbert   +11 more
wiley   +1 more source

Profiles of Medicaid Beneficiaries with Treatment-Resistant Depression Initiated on Esketamine Nasal Spray. [PDF]

open access: yesNeurol Ther
Clemens K   +8 more
europepmc   +1 more source

Feasibility and Acceptability of Brief Behavioral Treatment for Insomnia After Eating Disorder Treatment: The TIRED Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The purpose of this pilot trial was to evaluate the novel use of Brief Behavioral Treatment for Insomnia (BBTI) for people with residual insomnia disorder following eating disorder (ED) treatment. Methods Participants (N = 6) completed a multiple‐baseline design study of BBTI.
Kara A. Christensen Pacella   +4 more
wiley   +1 more source

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