Results 111 to 120 of about 25,296 (269)

Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces

open access: yesAdvanced Science, EarlyView.
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee   +9 more
wiley   +1 more source

Insomnia, Depression, and Physical Disorders in Late Life: A 2-year Longitudinal Community Study in Koreans

open access: yes, 2009
Study Objectives: To investigate prevalence, incidence, and persistence of insomnia, and their bidirectional longitudinal associations with depression and physical disorders. Design: A community based longitudinal study. Setting: Elders living in private
Yoon, Jin-Sang   +11 more
core   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

open access: yesAdvanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo   +14 more
wiley   +1 more source

The effectiveness of transdiagnostic cognitive behavioral therapy for comorbid insomnia: a case report

open access: yesIranian Journal of Psychiatry, 2018
Objective: Similar cognitive and behavioral factors underlie and perpetuate insomnia and emotional disorders. This brief case report aims to evaluate the effectiveness of the Unified Protocol (UP), a transdiagnostic treatment designed to target emotional
Hoda Doos Ali Vand   +4 more
doaj  

Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients.

open access: yes, 2010
Background: There is an increasing evidence that the Brain-Derived Neurotrophic Factor (BDNF) could be involved in the pathophysiology of mood disorders and that its peripheral levels may represent a reliable mirror of its concentration in the brain. The
BIANCHI, CAROLINA
core  

Bidirectional Relationship Between Dental Diseases and Sleep Disturbances in Pediatric Patients

open access: yes
Background Certain dental diseases in pediatric patients may disturb their sleep, affect their oral health‐related quality of life, and result in a negative influence on cognition and behavior.
Fangkai Han   +4 more
core   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

open access: yesAdvanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes   +15 more
wiley   +1 more source

Research progress on neural mechanisms of primary insomnia by MRI

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2018
In recent years, more and more researches focused on the neural mechanism of primary insomnia (PI), especially with the development and application of MRI, and researches of brain structure and function related with primary insomnia were more and more in-
Man WANG, Lu-ping SONG
doaj  

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Analysis of the relationship between insomnia and adult chronic diseases with regard to working conditions

open access: yesFamily Medicine & Primary Care Review, 2020
Weronika Wolińska   +2 more
doaj   +1 more source

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