Results 91 to 100 of about 25,289 (222)

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

Advanced Science, EarlyView.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li, Henghui Deng, Shiwei Yu, Jiawei Huang, Zehong Chen, Dawei Zhao, Chaoqun Zhang   +6 more
wiley   +1 more source

Self‐Powered All‐in‐One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps

Advanced Science, EarlyView.
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim, Tae Woog Kang, Hyunjoon Yoo, Jawon Ha, Yunuo Huang, Hee Han, Chi Won Ahn, Woon‐Hong Yeo, Il‐Kwon Oh   +8 more
wiley   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

AGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang, Bo Xie, Can Liu, Yifan Song   +3 more
wiley   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

Advanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan   +3 more
wiley   +1 more source

A Multimodal Intelligent System for Human Digital Twin Simulation with Continuous Kinematic Data Tracking, Biometric Prognosis, and Cognitive State Feedback in Industrial Environments

Advanced Intelligent Discovery, EarlyView.
This article implements a unified human digital twin framework that integrates cutting edge actuation, sensing, simulation, and bidirectional feedback capability. The approach includes integrating multimodal sensing, AI, and biomechanical simulation into one compact system.
Tajbeed Ahmed Chowdhury, Sebastian Gratz‐Kelly, Eric Wagner, Paul Motzki, Martina Lehser   +4 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source