Results 91 to 100 of about 68,116 (268)

Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]

, 2016
Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M., Kraft, Walter K., Stover, Megan W.   +2 more
core   +2 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Effects of social isolation on sleep during the COVID-19 pandemic [PDF]

Sleep Science
The current COVID-19 pandemic is a public health emergency that has seriously affected mental health in the general population. Both, studies on previous epidemics and those conducted during the current pandemic have reported a wide range of psychosocial
Franklin Escobar-Córdoba, Jairo Ramírez-Ortiz, Jeisson Fontecha-Hernández   +2 more
doaj   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Prolonged-Release Melatonin for Sleep Disturbances in Autism Spectrum Disorder [PDF]

Annals of Child Neurology
Purpose Patients with autism spectrum disorder (ASD) often present with sleep disturbances. We evaluated the effectiveness of pediatric prolonged-release melatonin (PedPRM) in real clinical practice, focusing on a population of complex neuropediatric ...
Eva Arias Vivas, Adrián García Ron, Elena González Alguacil, Marta Bote Gascón, María Teresa de Santos Moreno, Elsa Santana Cabrera, Guillermo Ruiz-Ocaña de las Cuevas, Juan José García Peñas, Rafael Sánchez-del Hoyo, Víctor Soto Insuga   +9 more
doaj   +1 more source

The motivating operation and negatively reinforced problem behavior. A systematic review. [PDF]

, 2014
The concept of motivational operations exerts an increasing influence on the understanding and assessment of problem behavior in people with intellectual and developmental disability. In this systematic review of 59 methodologically robust studies of the
Borthwick-Duffy S. A., Carey Y. A., Edrisinha C. E., Kennedy C. H., Miltenberger R. G., Oliver C., Rusch R. G., Scotti J. R.   +7 more
core   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Z-drug abuse and dependence: clinical guideline of the Brazilian Academy of Neurology for diagnosis and management

Arquivos de Neuro-Psiquiatria
Benzodiazepine (BZD) receptor agonists, commonly known as Z-drugs, are non-BZD hypnotics primarily prescribed for the treatment of insomnia. Their use is recommended for no longer than four weeks to minimize the risk of adverse effects, including ...
Fernando Gustavo Stelzer, Andrea Bacelar, Alan Luiz Éckeli, André Brooking Negrão, Carlos Maurício Oliveira Almeida, Clélia Maria Ribeiro Franco, Gabriel Natan Pires, Lívia Leite Goés Gitaí, Manoel Alves Sobreira-Neto, Márcia Assis, Paulo Afonso Mei, Rosa Hasan, Sandra Cristina Gonçalves Martinez, Tania Marchiori, Thiago M. Fidalgo, Luciana L. de Siqueira, Dalva Poyares   +16 more
doaj   +1 more source

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Interpretation of "Guidelines for the diagnosis and treatment of adult insomnia in China"

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
In order to standardize the diagnosis and treatment of adult insomnia in China, the sleep disorder study group of Chinese Medical Association Neuropathy Branch invited experts to discuss the issue repeatedly and compile the "Guidelines for the diagnosis ...
Peng ZHANG, Zhong-xin ZHAO
doaj