Results 101 to 110 of about 68,116 (268)

Sleep Quality among Medical Students of a Portuguese University

Revista Portuguesa de Psiquiatria e Saúde Mental
Introduction: Sleep is a complex physiological process shared by most living beings. Sleep disorders have been increasing exponentially. University students, particularly medical students, are especially vulnerable to this problem. However, the existing
Rita Ferreira, João Brás, Joana Fialho, Cristina Peixoto   +3 more
doaj   +1 more source

Are Insomnia Type Sleep Problems Associated With a Less Physically Active Lifestyle? A Cross-Sectional Study Among 7,700 Adults From the General Working Population

Frontiers in Public Health, 2019
Background: Sleep problems are common in the general population and negatively affect both private and work life. A vicious circle may exist between poor sleep and an unhealthy lifestyle.
Rúni Bláfoss, Emil Sundstrup, Markus Due Jakobsen, Hans Bay, Anne Helene Garde, Anne Helene Garde, Lars Louis Andersen, Lars Louis Andersen   +7 more
doaj   +1 more source

Disruption to control network function correlates with altered dynamic connectivity in the wider autism spectrum. [PDF]

, 2017
Autism is a common developmental condition with a wide, variable range of co-occurring neuropsychiatric symptoms. Contrasting with most extant studies, we explored whole-brain functional organization at multiple levels simultaneously in a large subject ...
Calhoun, VD, de Lacy, N, Doherty, D, King, BH, Rachakonda, S   +4 more
core   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Circadian regulation of reproduction: From gamete to offspring [PDF]

, 2013
P01326625; Grants: GNT0519315Few challenges are more critical to the survival of a species than reproduction. To ensure reproductive success, myriad aspects of physiology and behaviour need to be tightly orchestrated within the animal, as well as timed ...
Boden, M., Kennaway, D., Varcoe, T.
core   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Insomnia in patients undergoing Autologous Hematopoietic Stem Cell Transplantation

Infermieristica Journal
Background: Insomnia has an elevated incidence in patients who receive autologous Hematopoietic Stem Cell Transplantation (HSCT), which can lead to psychic and physical dysfunctions and impair immunological and neuroendocrine processes, hence ...
Mayra Veronese, Federica Lacarbonara
doaj   +1 more source

The 24 hour lung function time profile of olodaterol once daily versus placebo and tiotropium in patients with moderate to very severe chronic obstructive pulmonary disease [PDF]

, 2014
Background: Olodaterol is a once-daily long-acting β2-agonist being investigated for the treatment of chronic obstructive pulmonary disease, with ≥ 24 hour bronchodilator activity.
Aumann, Joseph-Leon, Derom, Eric, Hamilton, Alan, Lange, Peter, Tetzlaff, Kay, Ting, Naitee   +5 more
core   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Monitoring sleep depth: analysis of bispectral index (BIS) based on polysomnographic recordings and sleep deprivation [PDF]

, 2015
© 2015 Springer Science+Business Media Dordrecht The assessment and management of sleep are increasingly recommended in the clinical practice. Polysomnography (PSG) is considered the gold standard test to monitor sleep objectively, but some practical ...
Alonso López, Joan Francesc, Antonijoan Arbós, Rosa Maria, Baxarias, Pilar, Giménez Badia, Sandra, Mañanas Villanueva, Miguel Ángel, Pujol, Anna, Romero Lafuente, Sergio   +6 more
core   +2 more sources