Results 81 to 90 of about 272,474 (340)

Aging and the Spectral Properties of Brain Hemodynamics

open access: yesAdvanced Science, EarlyView.
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park   +9 more
wiley   +1 more source

Treatment guidelines for Circadian Rhythm Sleep - Wake Disorders of the Polish Sleep Research Society and the Section of Biological Psychiatry of the Polish Psychiatric Association. Part II. Diagnosis and treatment.

open access: yesPsychiatria Polska, 2017
AIM Circadian rhythm sleep-wake disorders (CRSWD) are a group of disorders, in which the timing of sleep and wakefulness significantly differs from a patient's expectations or socially acceptable times.
A. Wichniak   +7 more
semanticscholar   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

open access: yesAdvanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch   +13 more
wiley   +1 more source

Multi-Class SVM Based on Sleep Stage Identification Using EEG Signal [PDF]

open access: yes, 2015
Currently, sleep disorders are considered as one of the major human life issues. Human sleep is a regular state of rest for the body in which the eyes are not only usually closed, but also have several nervous centers being inactive; hence, rendering the
Aboalayon, Khald A.I., Faezipour, Miad
core   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

open access: yesAdvanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen   +13 more
wiley   +1 more source

The neurophysiologic basis of the human sleep–wake cycle and the physiopathology of the circadian clock: a narrative review

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
The objectives of this review were to explain the neurologic processes that control the human sleep–wake cycle as well as the pathophysiology of the human circadian clock.
Chidiebere Emmanuel Okechukwu
doaj   +1 more source

The efficacy of transcranial current stimulation techniques to modulate resting-state EEG, to affect vigilance and to promote sleepiness [PDF]

open access: yes, 2018
Transcranial Current Stimulations (tCSs) are non-invasive brain stimulation techniques which modulate cortical excitability and spontaneous brain activity by the application of weak electric currents through the scalp, in a safe, economic, and well ...
Alfonsi, Valentina   +3 more
core   +2 more sources

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20–75 Years of Age

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek   +8 more
wiley   +1 more source

The sleep cycle: a mathematical analysis from a global workspace perspective [PDF]

open access: yes, 2005
Dretske's technique of invoking necessary conditions from information theory to describe mental process can be used to derive a version of Hobson's AIM treatment of the sleep/wake cycle from a mathematical formulation of Baars' Global Workspace model of ...
Wallace, Rodrick
core  

Bright light therapy as part of a multicomponent management program improves sleep and functional outcomes in delirious older hospitalized adults. [PDF]

open access: yes, 2013
ObjectiveDelirium is associated with poor outcomes following acute hospitalization. A specialized delirium management unit, the Geriatric Monitoring Unit (GMU), was established.
Ancoli-Israel, Sonia   +4 more
core   +1 more source

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