Results 121 to 130 of about 707,629 (374)

Association Between Feeding Problems and Gastrointestinal Symptoms, Language, and Developmental History in Adults With Angelman Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Angelman syndrome (AS) is a neurodevelopmental disorder characterized by severe developmental delays, typical facial features, ataxia, seizures, speech impairments, sleeping difficulties, and a happy demeanor. Caregivers of individuals with AS often report feeding problems, with difficulties including issues with obesity, failure to gain ...
Ciara Cassidy, Arlene Mannion, Sally Whelan, Megan Tones, Helen Heussler, Matthew Bellgard, Geraldine Leader   +6 more
wiley   +1 more source

Detection of trypanosomes in suspected sleeping sickness patients in Uganda using the polymerase chain reaction

Bulletin of the World Health Organization
Diagnosis of sleeping sickness (trypanosomiasis) is difficult because of the fluctuating levels of parasitaemia encountered in patients. In the present study we found that the polymerase chain reaction (PCR) demonstrated trypanosome infection in 20 out ...
J.W Kyambadde, J.C.K Enyaru, E Matovu, M Odiit, J.F Carasco   +4 more
doaj   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +4 more sources

Sleeping Sickness Epidemics and Colonial Responses in East and Central Africa, 1900–1940

PLoS Neglected Tropical Diseases, 2014
In the early 20th centu- ry, major epidemics of trypanoso- miasis (sleeping sickness) broke out in East and Central Africa. The European colonial powers that controlled this area reacted by sending scientific missions to study the disease, establishing ...
D. Headrick
semanticscholar   +1 more source

An International ASXL3 Natural History Study: Deep Phenotypic Analyses Including Detailed Reports of a Milder Phenotype, Novel Associations, and Clinical Recommendations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Natural History Studies can help inform clinician and caregiver expectations, form the basis of management guidelines, and provide a comparator for therapeutic intervention. In rare conditions, where collection of prospective longitudinal data is untimely and impractical, quasi‐natural history data—from multiple individuals of different ages ...
E. Woods, N. Holmes, A. S. Denommé‐Pichon, M. Vincent, N. Belova, C. Gooch, B. Isidor, C. W. Ockeloen, E. Pavlidou, H. Stewart, V. J. M. Verhoeven, A. Ververi, A. Dixit, A. Sarkar, R. Legg, E. Reid, M. Balasubramanian   +16 more
wiley   +1 more source

African trypanosomes

Parasites & Vectors, 2019
African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa.
Mathieu Cayla, Federico Rojas, Eleanor Silvester, Frank Venter, Keith R. Matthews   +4 more
doaj   +1 more source

FITCA-EMMC workshops on information exchange and training with rural communities on environment: Eastern Uganda. W1 [PDF]

, 2003
Four workshops were held in four sub counties in the districts of Soroti, Tororo, Iganga and Kamuli. Five to seven villages were involved in each sub county.
Kang'Ethe, Erastus, Maitima, Joseph, Mbugua, Simon, Mbuvi, Dorcas, Toutain, Bernard   +4 more
core  

In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei [PDF]

, 2016
Background: African trypanosomes are the causative agents of sleeping sickness in humans and nagana disease in livestock animals. As the few drugs available for treatment of the diseases have limited efficacy and produce adverse reactions, new and better
A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Scherzad, Adam Huczyński, AH Fairlamb, D Steverding, DH Molyneux, Dietmar Steverding, E Matovu, GE Moore, H Hirumi, K Merschjohann, M Antoszczak, M Antoszczak, Michał Antoszczak, S Nwaka, SJ Collins, SV Barrett, T Baltz, V Delespaux, W Huber   +24 more
core   +1 more source

Performance of Parasitological and Molecular Techniques for the Diagnosis and Surveillance of Gambiense Sleeping Sickness

PLoS Neglected Tropical Diseases, 2014
Objectives Recently, improvements have been made to diagnostics for gambiense sleeping sickness control but their performance remains poorly documented and may depend on specimen processing prior to examination.
D. Mumba Ngoyi, Rosine Ali Ekangu, Marie France Mumvemba Kodi, P. Pyana, F. Balharbi, Mélanie Decq, Victor Kande Betu, W. Van der Veken, Claude Sese, J. Menten, P. Büscher, V. Lejon   +11 more
semanticscholar   +1 more source

Trisomy 5p: Long Recognized, Rarely Published‐ Three New Cases and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Complete trisomy 5p is a rare chromosomal disorder caused by a duplication of the short arm of chromosome 5. Current data suggest that complete trisomy 5p presents as a distinct clinical syndrome including but not limited to seizures, developmental delays, facial dysmorphisms, failure to thrive, and recurrent respiratory infections.
Gabriela J. Kim, Kristen N. Lee, Amanda B. Pritchard   +2 more
wiley   +1 more source