Results 131 to 140 of about 19,704 (280)

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

open access: yesChemistry – A European Journal, EarlyView.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret   +9 more
wiley   +1 more source

Advancing epidemiological modeling: spectral collocation for sleeping sickness

open access: yesDiscover Applied Sciences
While nonlinear ordinary differential equations (ODEs) are fundamental to epidemiological modeling, they require numerical solvers that are both accurate and stable over long-term simulations.
Oluwasegun M. Ibrahim, Piers W. Lawrence
doaj   +1 more source

Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients. [PDF]

open access: yesBMC Res Notes, 2022
Kato CD   +6 more
europepmc   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf   +9 more
wiley   +1 more source

Three Drug Combinations for Late-Stage Trypanosoma brucei gambiense Sleeping Sickness: A Randomized Clinical Trial in Uganda

open access: hybrid, 2006
Gérardo Priotto   +7 more
openalex   +2 more sources

Resilience Practices and Post‐Traumatic Growth Among Sudanese IDPs

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT In this paper we examine the resilience of internally displaced persons (IDPs) in Sudan who have endured various forms of suffering resulting from being targeted or trapped by militants involved in large‐scale violence. Upon escaping the conflict zones, the civilians exhibit strength, adaptability, and wisdom in the face of various threats to ...
Karina Korostelina   +2 more
wiley   +1 more source

Trypanososma brucei rhodesiense Sleeping Sickness, Uganda

open access: yesEmerging Infectious Diseases, 2012
Lea Berrang-Ford   +2 more
doaj   +1 more source

Plasma cytokines quantification among Trypanosoma brucei rhodesiense sleeping sickness cases and controls in Rumphi, Malawi. [PDF]

open access: yesMalawi Med J, 2021
Kamoto K   +7 more
europepmc   +1 more source

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