Results 141 to 150 of about 707,629 (374)

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp   +7 more
wiley   +1 more source

“That grey area where no one can help”: The experience of younger people avoiding or leaving residential aged care who are not NDIS participants

open access: yesAustralian Journal of Social Issues, EarlyView.
Abstract Living in residential aged care (RAC) can have deleterious effects on the health, well‐being and social participation of younger people (<65 years of age). This research examined the barriers and enablers to leaving or avoiding RAC for Australian younger people who are not National Disability Insurance Scheme (NDIS) participants. It reports on
Barrie Shannon   +3 more
wiley   +1 more source

Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated versus non-stimulated Glossina palpalis gambiensis flies

open access: yesFrontiers in Microbiology, 2015
The unicellular pathogenic protozoan Trypanosoma brucei gambiense is responsible for the chronic form of sleeping sickness. This vector-borne disease is transmitted to humans by the tsetse fly of the group Glossina palpalis, including the subspecies G. p.
Anne eGeiger   +6 more
doaj   +1 more source

Human African Trypanosomiasis (Sleeping Sickness)-Epidemiology, Clinical Manifestations, Diagnosis, Treatment, and Prevention. [PDF]

open access: yesCurr Trop Med Rep, 2023
Ortiz-Martínez Y   +4 more
europepmc   +1 more source

Minor groove binders: some recent research in drug development [PDF]

open access: yes, 2009
The role of the naturally occurring polyamides distamycin and netropsin as antibacterial agents is described. Also, the importance of the modifications to the lipophilic and hydrophobic moieties is discussed.
Khalaf, Abedawn I.
core  

SLEEPING SICKNESS AND GENERAL PARALYSIS [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1908
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openaire   +3 more sources

‘Somewhere We Can Call Home and…Be Normal’: Findings From the Justice Housing Programme Evaluation

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT The relationship between homelessness or unstable housing and reincarceration is well documented. The initial month after a person is released from custody is a period of particular vulnerability, with an increased risk of homelessness and return to prison.
Helen Taylor, Lorana Bartels
wiley   +1 more source

Examining the Impact of Domestic and Family Violence on Young Australians’ School‐Level Education

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Australian policy and practice increasingly acknowledges the need to respond to children as victim‐survivors of domestic and family violence (DFV) in their own right. As part of this, and in recognition that schools often have the most consistent contact with young people experiencing DFV, there is mounting recognition of the role education ...
Rebecca Stewart   +2 more
wiley   +1 more source

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