Results 181 to 190 of about 707,629 (374)

Special Issue “Drug Discovery of Antiprotozoal Agents”

Pharmaceuticals
Protozoal diseases, such as leishmaniasis, malaria, African sleeping sickness, Chagas disease, amoebiasis, giardiasis, cryptococcosis, and toxoplasmosis (among others), affect and/or have the potential to infect more than one billion people worldwide [...
Francisco Jaime Bezerra Mendonça-Junior
doaj   +1 more source

Prevalence of pathogenic trypanosome species in naturally infected cattle of three sleeping sickness foci of the south of Chad. [PDF]

PLoS One, 2022
Vourchakbé J, Tiofack AAZ, Kante ST, Barka PA, Simo G.   +4 more
europepmc   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Scaling up of tsetse control to eliminate Gambian sleeping sickness in northern Uganda. [PDF]

PLoS Negl Trop Dis, 2022
Hope A, Mugenyi A, Esterhuizen J, Tirados I, Cunningham L, Garrod G, Lehane MJ, Longbottom J, Mangwiro TC, Opiyo M, Stanton M, Torr SJ, Vale GA, Waiswa C, Selby R.   +14 more
europepmc   +1 more source

A Note on Sleeping Sickness in Principe Island and Angola, West Coast of Africa [PDF]

, 1913
Surgeon McCowen
openalex   +1 more source

Dose individualisation of antibiotics in critically ill patients with inflammation: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Due to extensive pathophysiological changes in critically ill patients, standard dosing of antibiotics may lead to inadequate drug exposure. This is concerning, as insufficient plasma drug concentrations may lead to treatment failure, whereas excessive drug exposure may increase the risk of toxic adverse events.
Sarah Dräger, Iris K. Minichmayr, Narges Alipanah‐Lechner, Erin F. Barreto, Lieuwe D. J. Bos, Lucas M. Fleuren, Nicole G. M. Hunfeld, Sumith K. Mathew, Sophie L. Stocker, João Paulo Telles, Antoni Torres, Birgit C. P. Koch, Henrik Endeman   +12 more
wiley   +1 more source

The Fight Against Sleeping Sickness 1 [PDF]

, 1910
E. A. M.
openalex   +1 more source

Does school matter for children's cognitive and non‐cognitive learning? Findings from a natural experiment in Pakistan and India

British Educational Research Journal, EarlyView.
Abstract This paper reports on the findings of a natural experiment based on a sample of 1123 children aged 4–8 from the provinces of Punjab in Pakistan, and Gujarat in India. It looks at the impact of attendance (or not) in early schooling on the cognitive and social–emotional development of young children.
Nadia Siddiqui, Stephen Gorard, Smruti Bulsari, Beng See, Pauline Dixon, Saba Saeed, Hamza Safaraz, Kiran Pandya   +7 more
wiley   +1 more source

APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin

Cell Reports, 2020
Summary: The C-terminal variants G1 and G2 of apolipoprotein L1 (APOL1) confer human resistance to the sleeping sickness parasite Trypanosoma rhodesiense, but they also increase the risk of kidney disease.
Sophie Uzureau, Laurence Lecordier, Pierrick Uzureau, Dorle Hennig, Jonas H. Graversen, Fabrice Homblé, Pepe Ekulu Mfutu, Fanny Oliveira Arcolino, Ana Raquel Ramos, Rita M. La Rovere, Tomas Luyten, Marjorie Vermeersch, Patricia Tebabi, Marc Dieu, Bart Cuypers, Stijn Deborggraeve, Marion Rabant, Christophe Legendre, Søren K. Moestrup, Elena Levtchenko, Geert Bultynck, Christophe Erneux, David Pérez-Morga, Etienne Pays   +23 more
doaj  

Structural Modelling of Platelet Activating Factor Acetyl Hydrolase in Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei: Implications on Therapeutics for Leishmaniasis, Chagas Disease, and Sleeping Sickness. [PDF]

Infect Drug Resist, 2023
Goswami A, Koley T, Rajan MV, Madhuri P, Upadhyay N, Das U, Kumar M, Ethayathulla AS, Hariprasad G.   +8 more
europepmc   +1 more source