Results 181 to 190 of about 21,177 (293)

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Thermo-related degeneration of stumpy forms of Trypanosoma brucei, the pathogen of African sleeping sickness. [PDF]

Adv Biotechnol (Singap)
Luo JY, Wang JF, Yang J, Zhang P, Hide G, Lai DH, Lun ZR.   +6 more
europepmc   +1 more source

Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective against Trypanosoma brucei Which Causes African Sleeping Sickness. [PDF]

Inorg Chem, 2022
Marchetti F, Tombesi A, Di Nicola C, Pettinari R, Verdicchio F, Crispini A, Scarpelli F, Baldassarri C, Marangoni E, Hofer A, Galindo A, Petrelli R.   +11 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda. [PDF]

BMC Vet Res
Muhanguzi D, Wasswa AT, Abila PP, Mugenyi A, Kakuru M, Abizera H, Ainebyoona S, Kansiime M, Amanyire W, Nkamwesiga J, Kimuda PM, Rascón-García K, Matovu E.   +12 more
europepmc   +1 more source

Sleeping Sickness Disrupts the Sleep-Regulating Adenosine System. [PDF]

J Neurosci, 2020
Rijo-Ferreira F, Bjorness TE, Cox KH, Sonneborn A, Greene RW, Takahashi JS.   +5 more
europepmc   +1 more source

Apparent density, trypanosome infection rates and host preference of tsetse flies in the sleeping sickness endemic focus of northwestern Uganda. [PDF]

BMC Vet Res, 2021
Opiro R, Opoke R, Angwech H, Nakafu E, Oloya FA, Openy G, Njahira M, Macharia M, Echodu R, Malinga GM, Opiyo EA.   +10 more
europepmc   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Modulation of succinyl-CoA:3-ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping sickness. [PDF]

Protein Sci
Mochizuki K, Inaoka DK, Fukuda K, Kurasawa H, Iyoda K, Nakai U, Harada S, Balogun EO, Bringaud F, Boshart M, Sakura T, Hirayama K, Kita K, Shiba T.   +13 more
europepmc   +1 more source

Free-ranging pigs identified as a multi-reservoir of Trypanosoma brucei and Trypanosoma congolense in the Vavoua area, a historical sleeping sickness focus of Côte d'Ivoire. [PDF]

PLoS Negl Trop Dis, 2021
Traoré BM, Koffi M, N'Djetchi MK, Kaba D, Kaboré J, Ilboudo H, Ahouty BA, Koné M, Coulibaly B, Konan T, Segard A, Kouakou L, De Meeûs T, Ravel S, Solano P, Bart JM, Jamonneau V.   +16 more
europepmc   +1 more source