Results 51 to 60 of about 3,687,402 (296)

A Peak Set with a Maximal Hausdorff Dimension on Each Slice

open access: yesComplex Analysis and Operator Theory, 2023
AbstractWe consider a bounded balanced strictly convex domain $$\Omega \subset {\mathbb {C}}^{d}$$ Ω ⊂ C d with $$C^{2}$$
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

OPTIMASI PARAMETER PROSES 3D PRINTING TERHADAP KELENGKUNGAN SOFT PNEUMATIC GRIPPER DENGAN MENGGUNAKAN FILAMENT EFLEX

open access: yesRekayasa Mesin
The emergence of 3D Printing technology has influenced several industries.3D Printing quickly produced mechanical components and prototype products with low production volumes.
Hasdiansah Hasdiansah   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Direct Slicing Approach For The Production Of Perfused Components By Laser Beam Melting

open access: yesSouth African Journal of Industrial Engineering, 2014
In this paper, laser beam melting technology is applied to the manufacture of defined porous metal structures using the exposure strategies of the machine manufacturer. It turns out that specific filter characteristics such as density, permeability, pore
Sehrt, Jan Torsten
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

AI-based framework for early detection and segmentation of green citrus fruits in orchards

open access: yesSmart Agricultural Technology
The detection and segmentation of tiny green citrus fruits in dense orchards play a vital role in modern farming, directly influencing yield prediction, resource management, and timely decision-making. This research presents a cutting-edge framework that
Manal El Akrouchi   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Match-Unity: Long-Form Text Matching With Knowledge Complementarity

open access: yesIEEE Access
Semantic text matching is a fundamental task in Natural Language Processing, with existing methods mainly focusing on short texts. However, handling long texts remains a challenge, as conventional approaches often involve slicing or keyword filtering ...
Zhiyi He   +6 more
doaj   +1 more source

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