Results 161 to 170 of about 3,458,134 (243)
In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley +1 more source
Biodegradable Microrobots for Active Navigation and Delivery on Ex Vivo Cardiac Models. [PDF]
Kirmizitas FC +9 more
europepmc +1 more source
Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham +3 more
wiley +1 more source
Optical Control of Actin Network Assembly on the Supported Lipid Bilayer. [PDF]
Yamamoto K, Miyazaki M.
europepmc +1 more source
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk +5 more
wiley +1 more source
Binding properties of sulfur to enable solvent-free fabrication of high-performance polymer-free sulfur-carbon positive electrodes. [PDF]
An Y +9 more
europepmc +1 more source
Seismic analysis and design of tunnels within fault ground: A review
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang +6 more
wiley +1 more source
Hierarchically Reinforced PDMS-Silica Coatings for Durable Superhydrophobicity. [PDF]
Mohapatra A, Ghosh S.
europepmc +1 more source
Tagawa, Kazuo, Muraki, Masayoshi
openaire +1 more source
To address seepage‐induced tunnel face collapse, this study develops a two‐phase double‐point MPM framework to capture large‐deformation hydro‐mechanical interactions. Incorporating a cementation‐based constitutive model with dynamic permeability updates, the model is successfully validated against saturated granular‐column collapse experiments ...
Yue Tong +6 more
wiley +1 more source

