Results 161 to 170 of about 3,458,134 (243)

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

open access: yesCytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Biodegradable Microrobots for Active Navigation and Delivery on Ex Vivo Cardiac Models. [PDF]

open access: yesAdv Healthc Mater
Kirmizitas FC   +9 more
europepmc   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

open access: yesCytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham   +3 more
wiley   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk   +5 more
wiley   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

open access: yesDeep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang   +6 more
wiley   +1 more source

Friction properties of friction modifiers under the partial EHL contacts (2nd report high slide/roll ratio condition)

open access: yesProceeding of Annual/Fall Meetings of the Japan Petroleum Institute, 2011
Tagawa, Kazuo, Muraki, Masayoshi
openaire   +1 more source

Probabilistic characterization of seepage‐induced tunnel face failure via a two‐phase double‐point material point method

open access: yesDeep Underground Science and Engineering, EarlyView.
To address seepage‐induced tunnel face collapse, this study develops a two‐phase double‐point MPM framework to capture large‐deformation hydro‐mechanical interactions. Incorporating a cementation‐based constitutive model with dynamic permeability updates, the model is successfully validated against saturated granular‐column collapse experiments ...
Yue Tong   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy