Results 81 to 90 of about 910,363 (405)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Improved fast global sliding mode control based on the exponential reaching law
Advances in Mechanical Engineering, 2017 In order to improve the control performance of the global sliding mode control method, a fast global sliding mode control method is proposed to accelerate the response of the system by changing the exponential decay function in the sliding surface as an ...
Chunbo Xiu +3 more
doaj +1 more source
Sliding mode and shaped input vibration control of flexible systems [PDF]
, 2008 Copyright [2008] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Gao, H, Hu, Q, Wang, Z
core +2 more sources
A Novel Fault-Tolerant Control Method for Robot Manipulators Based on Non-Singular Fast Terminal Sliding Mode Control and Disturbance Observer [PDF]
, 2020 Anh Tuan Vo, Hee‐Jun Kang
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Adaptive Higher-Order Sliding Mode Control for Islanding and Grid-Connected Operation of a Microgrid
Energies, 2018 Grid-connected and islanding operations of a microgrid are often influenced by system uncertainties, such as load parameter variations and unmodeled dynamics.
Yaozhen Han, Ronglin Ma, Jinghan Cui
doaj +1 more source
Low-power wind energy conversion system with variable structure control for DC grids [PDF]
, 2013 This paper presents a discussion on the use of variable structure control, i.e., sliding mode control, for improving the dynamic control performance of a low-power wind energy conversion system (WECS) that is connected to a DC microgrid. The sliding mode
Hui, RSY, Mok, KT, Tan, SC, Yang, Y
core +1 more source
Reduce energy loss with dynamic positioning controller for USV based on Hierarchical Sliding Mode Control [PDF]
, 2021 Nguyễn Trung Kiên +2 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Advances in Mechanical Engineering, 2017 A disturbance attenuation–based sliding mode control approach with an extended disturbance observer is proposed for systems with mismatched uncertainties. A novel adaptive sliding surface consisting of the disturbance estimation is presented to eliminate
Jianguo Guo +3 more
doaj +1 more source