Pathogens, 2022 Protein-protein interactions drive functions in eukaryotes that can be described by short linear motifs (SLiMs). Conservation of SLiMs help illuminate functional SLiMs in eukaryotic protein families. However, the simplicity of eukaryotic SLiMs makes them
Heidy Elkhaligy +2 more
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Viruses, 2021 Most viruses have small genomes that encode proteins needed to perform essential enzymatic functions. Across virus families, primary enzyme functions are under functional constraint; however, secondary functions mediated by exposed protein surfaces that ...
Heidy Elkhaligy +2 more
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The eukaryotic linear motif resource – 2018 update [PDF]
Nucleic Acids Research, 2018 Short linear motifs (SLiMs) are protein binding modules that play major roles in almost all cellular processes. SLiMs are short, often highly degenerate, difficult to characterize and hard to detect.
Marc R Gouw +2 more
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Integrating AlphaFold2 models and clinical data to improve the assessment of Short Linear Motifs (SLiMs) and their variants' pathogenicity. [PDF]
PLoS Computational BiologyShort Linear Motifs (SLiMs) are protein functionally relevant regions that mediate reversible protein-protein interactions. Variants that disrupt SLiMs can lead to numerous Mendelian diseases.
Franco Gino Brunello +3 more
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ISO 9126 Untuk Pengujian Kualitas Aplikasi Perpustakaan Senayan Library Management System (SLiMS) [PDF]
Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2018 Perkembangan sistem informasi yang cepat telah membuat perubahan hampir di semua bidang kegiatan manusia, termasuk pengelolaan perpustakaan di perguruan tinggi.
Petrus Dwi Ananto Pamungkas
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Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo [PDF]
eLife, 2015 Hox proteins are well-established developmental regulators that coordinate cell fate and morphogenesis throughout embryogenesis. In contrast, our knowledge of their specific molecular modes of action is limited to the interaction with few cofactors. Here,
Manon Baëza +8 more
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Decoding phospho-regulation and flanking regions in autophagy-associated short linear motifs [PDF]
Communications BiologyShort Linear Motifs (SLiMs) play a pivotal role in the interactions between intrinsically disordered proteins and their binding partners. SLiMs can undergo regulation through post-translational modifications, including phosphorylation.
Mattia Utichi +7 more
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The leader proteins of Theiler’s virus and Boone cardiovirus use a combination of short linear motifs (SLiMs) to target RSK kinases to the nuclear pore complex [PDF]
Journal of VirologyUnrelated pathogens, including viruses and bacteria, use a common short linear motif (SLiM) to interact with cellular kinases of the RSK (p90 S6 ribosomal kinase) family.
Belén Lizcano-Perret +6 more
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Automatic, context-specific generation of Gene Ontology slims
BMC Bioinformatics, 2010 Background The use of ontologies to control vocabulary and structure annotation has added value to genome-scale data, and contributed to the capture and re-use of knowledge across research domains.
Melissa J Davis, Mark A Ragan
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The Use of SLiMS in The Circle of School Librarians in Semarang City
Record and Library Journal, 2021 Background of the study: Utilization of technology at this time is urgently needed in a job. Library is one of the jobs that requires technology. The technology used in school libraries has several types, one of which is SLiMS.
Ario Adi Prakoso
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