Results 111 to 120 of about 2,508,126 (264)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Reconstruction of Quaternary ELA of the Zagros Geomorphic Unit of Iran [PDF]
جغرافیا و پایداری محیط, 2018 Although the quaternary period is a very short period among the periods of geology, it is important for geomorphologists. The main objectives of this article are to provide the best method to estimate the ELA, analyze the effect of the change of latitude
Gholamhasan Jafari , Nasrin Hazrati
doaj
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
A review of earthquake-induced loess landslides research and future prospects
Zhongguo dizhi zaihai yu fangzhi xuebaoThe loess region is characterized by complex geomorphological patterns. This region is prone to frequent earthquakes with serious seismic landslide disasters.
Faqiao QIAN +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
PlantsTall fescue (Festuca arundinacea Schreb.) is a herbaceous species that is commonly used for ecological slope restoration in China. However, water scarcity often constrains its growth due to the unique site conditions of steep slopes and climate-induced ...
Meng Li +7 more
doaj +1 more source
Factors affecting handling qualities of a lift-fan aircraft during steep terminal area approaches [PDF]
The XV-5B lift-fan aircraft was used to explore the factors affecting handling qualities in the terminal area. A 10 deg ILS approach task was selected to explore these problems.
Gerdes, R. M., Hynes, C. S.
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source