Results 71 to 80 of about 94,811 (302)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Which Way Do You Lean?: Using Slope Aspect Variations to Understand Critical Zone Processes and Feedbacks

, 2018
Soil‐mantled pole‐facing hillslopes on Earth tend to be steeper, wetter, and have more vegetation cover compared with adjacent equator‐facing hillslopes.
Poulos, Michael J.
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

IDENTIFICATION OF PLANT SPECIES AND THEIR RELATIONSHIP WITH ALTITUDE AND SLOPE ASPECT: A CASE STUDY FROM NAINI LAKE CATCHMENT, CENTRAL HIMALAYA

Geography, Environment, Sustainability, 2019
In the Himalaya diversity of plant species is very rich in length and breadth of its spatial extent. Study area forms a part of the Central Himalaya where altitude is varying in between 1940m to 2615m.
Anil Fartiyal, Masoom Reza, R. C. Joshi, Ira Tiwari   +3 more
doaj   +1 more source

On the Slope-Aspect Correction of Multispectral Scanner Data

Canadian Journal of Remote Sensing, 1982
SUMMARYThe effects of topography on the radiometric properties of multispectral scanner (MSS) data are examined in the context of the remote sensing of forests in mountainous regions. The two test areas considered for this study are located in the coastal mountains of British Columbia, one at the Anderson River near Boston Bar and the other at Gun Lake
Teillet, P. M., Guindon, B., Goodenough, D. G.   +2 more
openaire   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Slope aspect affects the non-structural carbohydrates and C:N:P stoichiometry of Artemisia sacrorum on the Loess Plateau in China

, 2017
Slope aspect, as an important topographic factor on the Loess Plateau in China, may influence the productivity and relative characteristics of Artemisia sacrorum in this area. Three slope aspects (sunny, half-sunny, and shady slopes) were chosen to study
Liu, Guobin, Xue, S (reprint author), Inst Soil & Water Conservat, Xinong Rd 26, Yangling 712100, Shaanxi, Peoples R China., He, Lirong, Xue, Sha, Ai, Zemin, Xin, Qi, Yang, Ting   +6 more
core   +1 more source

Micrometeorological and morphological observations of surface hoar dynamics on a mountain snow cover [PDF]

, 2010
The formation, growth, and destruction of surface hoar crystals is an important feature of mountain snow covers as buried surface hoar layers are a frequent weak layer leading to unstable snowpacks.
C. Manes, C. Fierz, Lehning, Manes, Costantino, STOESSEL F, Lehning, M., GUALA M, Guala, M., M. Lehning, M, Manes, C., Fierz, C., FIERZ C, F. Stössel, M. Guala, Stossel, F., Lehning, Michael, Stoessel, F.   +17 more
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Elevation, slope and aspect data derived from the 3D topographic reconstruction.

, 2013
(a) Elevation above maximum low tide (b) slope of the terrain and (c) aspect of the terrain.
Daniel Bongiorno (461024), Mitch Bryson (461022), Richard J. Murphy (461023), Matthew Johnson-Roberson (294309)   +3 more
core   +1 more source