Results 31 to 40 of about 187,260 (305)

Three-dimensional limit equilibrium method for rock slopes by constructing normal stress distribution over sliding surface and its application

open access: yesYantu gongcheng xuebao
The researches on the three-dimensional stability of rock slopes are of important theoretical significance and engineering application prospect. The conventional equivalent Mohr-Coulomb strength parameters used to analyze the stability of rock slopes ...
LU Kunlin 1, MEI Yifan 1, WANG Linfei 2, JIA Senlin 1, QIN Tao 1, ZHU Dayong 3
doaj   +1 more source

Slope Stability Analysis Using a Self-Adaptive Genetic Algorithm [PDF]

open access: yesJournal of Hydraulic Structures, 2016
This paper introduces a methodology for soil slope stability analysis based on optimization, limit equilibrium principles and method of slices. In this study, the slope stability analysis problem is transformed into a constrained nonlinear optimization ...
Amir H. Ayati   +2 more
doaj   +1 more source

Time-dependent stability analysis of open-pit slope considering life-cycle

open access: yes矿业科学学报, 2021
Based on the influence of excavation and creep degradation on the stability of high slopes in open-pit, a stability model of slopes in life-cycle is proposed.
Bao Min   +4 more
doaj   +1 more source

Evaluation of slope stability with topography and slope stability analysis method

open access: yesKSCE Journal of Civil Engineering, 2011
In existing researches connected with landslide, natural slope was regard as a parallel slope, but it was found that many landslides were occurred on the concave and convex slopes besides parallel slopes. This study was performed to evaluate the effect of shape and length of slope and soil depth for slope stability analysis and to compare infinite ...
Kyung-Seob Cha, Tae-Hoon Kim
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Slope stability analysis [PDF]

open access: yes
Slope stability analysis can be undertaken using a variety of methods and software packages. Each method makes different assumptions in order to solve the slope stability problem, and there is much debate over which method is the recommended method to use for certain situations.
  +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Coupled effects of earthquake and rainfall on landslide susceptibility in non-tropical coastal areas: assessing governing mechanisms and innovative slope protection strategy

open access: yesDiscover Civil Engineering
Despite extensive research on landslides globally, there is a notable knowledge gap on mechanisms influenced by combined rainfall and earthquake events to induce landslides in non-tropical coastal areas, and how to mitigate such failures.
Prabhakar Khadka   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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